A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.
…, MA Zanta, MD Mergny, D Scherman… - Proceedings of the …, 1995 - National Acad Sciences
Several polycations possessing substantial buffering capacity below physiological pH, such
as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--ie…
as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--ie…
The in vivo activation of persistent nanophosphors for optical imaging of vascularization, tumours and grafted cells
…, P Dorenbos, M Bessodes, D Gourier, D Scherman… - Nature materials, 2014 - nature.com
Optical imaging for biological applications requires more sensitive tools. Near-infrared
persistent luminescence nanoparticles enable highly sensitive in vivo optical detection and …
persistent luminescence nanoparticles enable highly sensitive in vivo optical detection and …
Protective role of interleukin-10 in atherosclerosis
…, C Fievet, B Staels, N Duverger, D Scherman… - Circulation …, 1999 - Am Heart Assoc
The potential role of anti-inflammatory cytokines in the modulation of the atherosclerotic
process remains unknown. Interleukin (IL)-10 has potent deactivating properties in …
process remains unknown. Interleukin (IL)-10 has potent deactivating properties in …
High-efficiency gene transfer into skeletal muscle mediated by electric pulses
…, B Schwartz, D Scherman - Proceedings of the …, 1999 - National Acad Sciences
Gene delivery to skeletal muscle is a promising strategy for the treatment of muscle disorders
and for the systemic secretion of therapeutic proteins. However, present DNA delivery …
and for the systemic secretion of therapeutic proteins. However, present DNA delivery …
Nanoprobes with near-infrared persistent luminescence for in vivo imaging
…, D Gourier, M Bessodes, D Scherman - Proceedings of the …, 2007 - National Acad Sciences
Fluorescence is increasingly used for in vivo imaging and has provided remarkable results.
Yet this technique presents several limitations, especially due to tissue autofluorescence …
Yet this technique presents several limitations, especially due to tissue autofluorescence …
Controlling electron trap depth to enhance optical properties of persistent luminescence nanoparticles for in vivo imaging
Focusing on the use of nanophosphors for in vivo imaging and diagnosis applications, we
used thermally stimulated luminescence (TSL) measurements to study the influence of …
used thermally stimulated luminescence (TSL) measurements to study the influence of …
Synthesis, activity, and structure− activity relationship studies of novel cationic lipids for DNA transfer
…, P Wils, B Schwartz, D Scherman - Journal of medicinal …, 1998 - ACS Publications
We have designed and synthesized original cationic lipids for gene delivery. A synthetic
method on solid support allowed easy access to unsymmetrically monofunctionalized …
method on solid support allowed easy access to unsymmetrically monofunctionalized …
Striatal dopamine deficiency in Parkinson's disease: role of aging
D Scherman, C Desnos, F Darchen… - Annals of Neurology …, 1989 - Wiley Online Library
The striatal dopaminergic innervation was investigated postmortem in 49 control and 57
parkinsonian brains by assessing the binding of tritiated α‐dihydrotetrabenazine ([ 3 H]TBZOH), …
parkinsonian brains by assessing the binding of tritiated α‐dihydrotetrabenazine ([ 3 H]TBZOH), …
Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency
P Kreiss, P Mailhe, D Scherman, B Pitard… - Nucleic acids …, 1999 - academic.oup.com
Clinical applications of gene therapy mainly depend on the development of efficient gene
transfer vectors. Large DNA molecules can only be transfected into cells by using synthetic …
transfer vectors. Large DNA molecules can only be transfected into cells by using synthetic …
Storage of visible light for long-lasting phosphorescence in chromium-doped zinc gallate
…, T Maldiney, C Richard, D Scherman… - Chemistry of …, 2014 - ACS Publications
ZnGa 2 O 4 :Cr 3+ presents near-infrared long-lasting phosphorescence (LLP) suitable for
in vivo bioimaging. It is a bright LLP material showing a main thermally stimulated …
in vivo bioimaging. It is a bright LLP material showing a main thermally stimulated …