User profiles for David R. Grimm
David GrimmStanford University Verified email at stanford.edu Cited by 361 |
ABT-888, an orally active poly (ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
…, NS Ghoreishi-Haack, DR Grimm, R Guan… - Clinical cancer …, 2007 - AACR
Purpose: To evaluate the preclinical pharmacokinetics and antitumor efficacy of a novel
orally bioavailable poly(ADP-ribose) polymerase (PARP) inhibitor, ABT-888. Experimental …
orally bioavailable poly(ADP-ribose) polymerase (PARP) inhibitor, ABT-888. Experimental …
Resistive inspiratory muscle training in subjects with chronic cervical spinal cord injury
…, AM Spungen, WA Bauman, DR Grimm - Archives of physical …, 1998 - Elsevier
Objective: To determine whether pulmonary function, respiratory muscle strength, and
dyspnea can be improved in individuals with chronic cervical spinal cord injury (SCI). Study …
dyspnea can be improved in individuals with chronic cervical spinal cord injury (SCI). Study …
Sympathovagal balance of the heart in subjects with spinal cord injury
DR Grimm, RE De Meersman… - American Journal …, 1997 - journals.physiology.org
This study investigated the effect of abnormal autonomic cardiovascular function on heart
rate variability (HRV) in individuals classified into four groups: complete quadriplegia, …
rate variability (HRV) in individuals classified into four groups: complete quadriplegia, …
Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics
Objective Our objective was to learn whether genetic polymorphisms of metabolic enzymes
or transport proteins provide a mechanistic understanding of the in vivo disposition of …
or transport proteins provide a mechanistic understanding of the in vivo disposition of …
Psychological and autonomic effects of art making in college-aged students
…, EE Lodge, GC Kuns, DR Grimm - Anxiety, Stress, & …, 2016 - Taylor & Francis
Background and objectives: Anxiety disorders comprise the most common category of mental
illness among US young adults. Art making might be one method to help reduce anxiety, …
illness among US young adults. Art making might be one method to help reduce anxiety, …
Effects of autonomic disruption and inactivity on venous vascular function
…, JP Weir, WA Bauman, DR Grimm - American Journal …, 2000 - journals.physiology.org
The effects of autonomic disruption and inactivity were studied on the venous vascular system.
Forty-eight subjects, 24 with spinal cord injury (SCI) and 12 sedentary and 12 active able-…
Forty-eight subjects, 24 with spinal cord injury (SCI) and 12 sedentary and 12 active able-…
Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies
…, A Ferrajoli, M Albitar, E McKeegan, DR Grimm… - Clinical Cancer …, 2005 - AACR
Purpose: ABT-751 is an oral antimitotic agent that binds to the colchicine site on β-tubulin. A
phase 1 study was conducted to determine the maximum tolerated dose and toxicities of …
phase 1 study was conducted to determine the maximum tolerated dose and toxicities of …
Virgin β-cells at the neogenic niche proliferate normally and mature slowly
…, J Zhang, S Saravanakumar, MF Flisher, DR Grimm… - Diabetes, 2021 - Am Diabetes Assoc
Proliferation of pancreatic β-cells has long been known to reach its peak in the neonatal
stages and decline during adulthood. However, β-cell proliferation has been studied under the …
stages and decline during adulthood. However, β-cell proliferation has been studied under the …
Assessment of airway caliber and bronchodilator responsiveness in subjects with spinal cord injury
GJ Schilero, DR Grimm, WA Bauman, R Lenner… - Chest, 2005 - Elsevier
Study objectives Previous spirometric findings among subjects with chronic tetraplegia that
reduction in FEV 1 and maximal forced expiratory flow, mid-expiratory phase (FEF 25–75% ) …
reduction in FEV 1 and maximal forced expiratory flow, mid-expiratory phase (FEF 25–75% ) …
Airway hyperreactivity in subjects with tetraplegia is associated with reduced baseline airway caliber
DR Grimm, D Chandy, PL Almenoff, G Schilero… - Chest, 2000 - Elsevier
Objectives We administered aerosolized histamine to 32subjects with tetraplegia to determine
whether there were differencesin spirometric and/or lung volume parameters between …
whether there were differencesin spirometric and/or lung volume parameters between …