[HTML][HTML] Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice
…, M Derrien, DJ Lindenbergh-Kortleve… - Mucosal …, 2012 - Elsevier
During colonization of germfree mice with the total fecal microbial community of their
conventionally born and raised siblings (conventionalization), the intestinal mucosal immune …
conventionally born and raised siblings (conventionalization), the intestinal mucosal immune …
Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage
…, N Papazian, DJ Lindenbergh-Kortleve… - Journal of Experimental …, 2015 - rupress.org
Disruption of the intestinal epithelial barrier allows bacterial translocation and predisposes
to destructive inflammation. To ensure proper barrier composition, crypt-residing stem cells …
to destructive inflammation. To ensure proper barrier composition, crypt-residing stem cells …
Contributions of mucosal immune cells to methotrexate-induced mucositis
…, JM van Dieren, DJ Lindenbergh-Kortleve… - International …, 2006 - academic.oup.com
The use of high doses of the anti-cancer drug methotrexate (MTX) is associated with
intestinal damage. As a result, mucosal immune cells become increasingly exposed to a vast …
intestinal damage. As a result, mucosal immune cells become increasingly exposed to a vast …
[HTML][HTML] Insulin-like growth factor-I and its receptor in neovascular age-related macular degeneration
…, KHM van Wely, DJ Lindenbergh-Kortleve… - … & visual science, 2003 - arvojournals.org
purpose. The insulin-like growth factor (IGF)-I protein is a growth-promoting polypeptide that
can act as an angiogenic agent in the eye. The purpose of the current study was to localize …
can act as an angiogenic agent in the eye. The purpose of the current study was to localize …
The IGF system during fetal-placental development of the mouse
…, C Groffen, DJ Lindenbergh-Kortleve… - Molecular and cellular …, 1998 - Elsevier
Insulin-like growth factors (IGF-I and -II) promote cellular mitosis and differentiation and
have been implicated in fetal and placental growth. Together with the IGF receptors and IGF …
have been implicated in fetal and placental growth. Together with the IGF receptors and IGF …
Human intestinal PEPT1 transporter expression and localization in preterm and term infants
…, BEA de Koning, DJ Lindenbergh-Kortleve… - Drug Metabolism and …, 2016 - ASPET
The intestinal influx oligopeptide transporter peptide transporter 1 (PEPT1) (SLC15A1) is
best known for nutrient-derived di- and tripeptide transport. Its role in drug absorption is …
best known for nutrient-derived di- and tripeptide transport. Its role in drug absorption is …
[HTML][HTML] Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis
…, R Boisgard, DJ Lindenbergh-Kortleve… - Mucosal …, 2021 - Elsevier
Single genetic mutations predispose to very early onset inflammatory bowel disease (VEO-IBD).
Here, we identify a de novo duplication of the 10p15.1 chromosomal region, including …
Here, we identify a de novo duplication of the 10p15.1 chromosomal region, including …
[HTML][HTML] Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes
…, MA Sanders, EMP Cremers, DJ Lindenbergh-Kortleve… - Leukemia, 2019 - nature.com
Highlights Activation of NF-κB signaling in mesenchymal cells is common in LR-MDS. Activation
of NF-κB in mesenchymal cells leads to transcriptional overexpression of inflammatory …
of NF-κB in mesenchymal cells leads to transcriptional overexpression of inflammatory …
Gene expression of the insulin-like growth factor system during mouse kidney development
DJ Lindenbergh-Kortleve, RR Rosato… - Molecular and cellular …, 1997 - Elsevier
Expression of the insulin-like growth factor (IGF) system was investigated in mouse renal
development and physiology, using non radioactive in situ hybridization and quantitative RT-…
development and physiology, using non radioactive in situ hybridization and quantitative RT-…
mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization
…, JW Van Neck, DJ Lindenbergh-Kortleve… - Molecular and cellular …, 1998 - Elsevier
During limb development the primary limb bud requires various signals to differentiate.
Insulin-like growth factor (IGF)-I and IGF-II serve as ubiquitous cellular growth promoters and are …
Insulin-like growth factor (IGF)-I and IGF-II serve as ubiquitous cellular growth promoters and are …