An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

…, S Trump, T Schumacher, L Jestaedt, D Schrenk… - Nature, 2011 - nature.com
Activation of the aryl hydrocarbon receptor (AHR) by environmental xenobiotic toxic chemicals,
for instance 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin), has been implicated in a variety …

Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.

…, L Poellinger, S Safe, D Schrenk… - Environmental …, 1998 - ehp.niehs.nih.gov
An expert meeting was organized by the World Health Organization (WHO) and held in
Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic …

Bioactive compounds: Definition and assessment of activity

…, I Elmadfa, R Grossklaus, M Müller, D Schrenk… - Nutrition, 2009 - Elsevier
Biomarkers and their role in evaluating efficacy and safety were the topic of the 23rd
Hohenheim Consensus Meeting at the University of Hohenheim in Stuttgart. Scientists who had …

Risk to human health related to the presence of perfluoroalkyl substances in food

…, D Schrenk… - EFSA …, 2020 - Wiley Online Library
The European Commission asked EFSA for a scientific evaluation on the risks to human health
related to the presence of perfluoroalkyl substances ( PFAS s) in food. Based on several …

Polybrominated Dibenzo-p-Dioxins, Dibenzofurans, and Biphenyls: Inclusion in the Toxicity Equivalency Factor Concept for Dioxin-Like Compounds

…, H Fiedler, J Falandysz, M Rose, D Schrenk… - toxicological …, 2013 - academic.oup.com
In 2011, a joint World Health Organization (WHO) and United Nations Environment
Programme (UNEP) expert consultation took place, during which the possible inclusion of …

Impact of dioxin-type induction of drug-metabolizing enzymes on the metabolism of endo-and xenobiotics.

D Schrenk - Biochemical pharmacology, 1998 - europepmc.org
The induction of a number of drug-metabolizing enzymes is among the best-understood
biochemical effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and related agonists of the …

Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals

…, JR Schlatter, V Silano, SS Nielsen, D Schrenk… - Efsa …, 2019 - Wiley Online Library
This Guidance document describes harmonised risk assessment methodologies for combined
exposure to multiple chemicals for all relevant areas within EFSA's remit, ie human health, …

The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds

…, L Haws, M Rose, S Safe, D Schrenk… - Toxicological …, 2006 - academic.oup.com
In June 2005, a World Health Organization (WHO)-International Programme on Chemical
Safety expert meeting was held in Geneva during which the toxic equivalency factors (TEFs) …

Guidance on technical requirements for regulated food and feed product applications to establish the presence of small particles including nanoparticles

…, H Naegeli, S Nielsen, J Schlatter, D Schrenk… - EFSA …, 2021 - Wiley Online Library
Following a mandate from the European Commission, EFSA has developed a Guidance on
Technical Requirements (Guidance on Particle‐ TR ), defining the criteria for assessing the …

Risk assessment of ochratoxin A in food

…, D Schrenk… - EFSA …, 2020 - Wiley Online Library
The European Commission asked EFSA to update their 2006 opinion on ochratoxin A ( OTA
) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and found as a …