Background Usher syndrome is the most common cause of deaf-blindness, affecting up to 1
in 6000 people. Multidisciplinary care is required to maximize outcomes for individuals and …

Immunotherapy with antigen-processing independent T cell epitopes (apitopes) targeting
autoreactive CD4 + T cells has translated to the clinic and been shown to modulate …

The enantiomeric composition of benoxaprofen [(RS)-2-(P-chlorophenyl)-alpha-methyl-5-benzoxazoleacetic
acid] in plasma and urine was determined after oral administration of both …

In vitro induced Foxp3 + T regulatory (iTreg) cells form a novel and promising target for
therapeutic tolerance induction. However, the potential of these cells as a target for the treatment …

… prepared by the method of Shepard and Noth (1). Homoveratrylamine was supplied by the
Monsanto Chemical Company. … ER SHEPARD, HD PORTER, JF NOTH, AND CK SIMMANS …

Background Advancements in genetic testing have led to Usher syndrome now being diagnosed
at a much earlier age than in the past, enabling the provision of early intervention and …

The general interest in the germicidal action of higher molecular weight quaternary ammonium
salts which has followed the introduction of this type of compound into the medicinal field …

The investigation of papaverine-like isoquinolines has been extended to the 3-methyl
compounds (I). During the course of preparing the intermediate phenylisopropylamines, two …

T regulatory (Treg) cells expressing the transcription factor FoxP3 play a key role in protection
against autoimmune disease. GFP-FoxP3 reporter mice have been used widely to study …

Substituted 2-bromopyridines have been oxi-dized to the corresponding 2-bromopyridine-N-oxides
by perbenzoic acid or peracetic acid. The labilized bromine atom was readily …