Pharmacokinetics, metabolism, and excretion of linezolid following an oral dose of [14C] linezolid to healthy human subjects

…, PE Fagerness, RP Stryd, GW Peng, EM Shobe - Drug Metabolism and …, 2001 - ASPET
Linezolid (Zyvox), the first of a new class of antibiotics, the oxazolidinones, is approved for
treatment of Gram-positive bacterial infections, including resistant strains. The disposition of …

Predicting oral absorption of drugs: a case study with a novel class of antimicrobial agents

…, JM Friis, J Palandra, JD Hosley, EM Shobe… - Pharmaceutical …, 2003 - Springer
Purpose. The purpose of this work was to evaluate an oral absorption prediction model,
maximum absorbable dose (MAD), which predicts a theoretical dose of drug that could be …

Nitrogen− Carbon-Linked (Azolylphenyl) oxazolidinones with Potent Antibacterial Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae …

…, D Stapert, BH Yagi, JM Friis, EM Shobe… - Journal of medicinal …, 1998 - ACS Publications
The emergence of multidrug-resistant strains of Grampositive bacterial pathogens is a
problem of ever increasing significance. 1-3 Organisms including methicillinresistant …

Rapid determination of rat plasma uridine levels by HPLC‐ESI‐MS utilizing the Captiva™ filter plates for sample preparation

…, J Palandra, EM Shobe - Biomedical …, 2003 - Wiley Online Library
A rapid, accurate and precise HPLC‐ESI‐MS method for the determination of rat plasma
uridine concentrations was developed and is described here. Sample preparation involves …

Thromboxane and prostacyclin production in ponies with colonic volvulus

…, WA Arden, RA Robinson, EM Shobe… - American journal of …, 1992 - Am Vet Med Assoc
Effects of 1 hour of colonic volvulus and 3 hours of reperfusion on concentrations of
thromboxane ( txb 2 ) and prostacyclin (6-keto-PGF lα ) in portal, pulmonary arterial, and jugular …

Development of a sensitive bioanalytical method for determination of PNU-83757 in rat, monkey and human plasma: from LC-UV to LC-MS/MS

MG Williams, EM Shobe, BE Bothwell… - Journal of pharmaceutical …, 2002 - Elsevier
To support pre-clinical pharmacokinetic/toxicokinetic (PK/TK) evaluation, a sensitive
bioanalytical method for determination of N-cyano-N′-(tert-pentyl)-N″-(3-pyridinyl) guanidine (…

Influence of handedness and bilateral eye movements on creativity

ER Shobe, NM Ross, JI Fleck - Brain and Cognition, 2009 - Elsevier
… bilateral EM participants during a 90 s episodic retrieval task. Because we observed limited
effects of bilateral EM on creativity, even for strong-handers, we wondered if the EM effect …

[PDF][PDF] Journal publications

…, K Ross, E Myers, D Norton, E Press, EM Shobe… - Energy, 2009 - researchgate.net
… “An Experimental Analysis of Auctioning Emissions Allowances under a Loose Cap,” (with
William Shobe, Erica Myers, Charles Holt, Jacob Goeree and Dallas Burtraw), Agricultural …

Assets, future orientation, and well-being: Exploring and extending Sherraden's framework

M Shobe, D Page-Adams - J. Soc. & Soc. Welfare, 2001 - HeinOnline
… Finally, asset accumulation in the form of employer-subsidized pension plans are often not
available to lowwage workers. This means that the working poor are discouraged from saving …

Molecular and cellular approaches to memory allocation in neural circuits

AJ Silva, Y Zhou, T Rogerson, J Shobe, J Balaji - Science, 2009 - science.org
Although memory allocation is a subject of active research in computer science, little is
known about how the brain allocates information within neural circuits. There is an extensive …