Structural and functional studies of UDP-glucuronosyltransferases

…, PJ Czernik, JM Little, E Battaglia… - Drug metabolism …, 1999 - Taylor & Francis
UDP–Glucuronosyltransferases (UGTs) are glycoproteins localized in the endoplasmic
reticulum (ER) which catalyze the conjugation of a broad variety of lipophilic aglycon substrates …

Control of oxidative posttranslational cysteine modifications: from intricate chemistry to widespread biological and medical applications

C Jacob, E Battaglia, T Burkholz, D Peng… - Chemical research in …, 2012 - ACS Publications
Cysteine residues in proteins and enzymes often fulfill rather important roles, particularly in
the context of cellular signaling, protein–protein interactions, substrate and metal binding, …

Regioselective and stereospecific glucuronidation of trans-and cis-resveratrol in human

V Aumont, S Krisa, E Battaglia, P Netter… - Archives of biochemistry …, 2001 - Elsevier
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a polyphenol present in wine, which has
been reported to have anti-inflammatory, anti-platelet, and anti-carcinogenic effects. The …

[HTML][HTML] Effects of endocrine disruptor compounds, alone or in combination, on human macrophage-like THP-1 cell response

N Couleau, J Falla, A Beillerot, E Battaglia… - PLoS …, 2015 - journals.plos.org
The aim of the present study was to evaluate the immunological effects on human macrophages
of four endocrine disruptor compounds (EDCs) using the differentiated human THP-1 …

The histone deacetylase inhibitor sodium butyrate induces breast cancer cell apoptosis through diverse cytotoxic actions including glutathione depletion and oxidative …

…, L Brault, S Osbild, E Battaglia… - International …, 2004 - spandidos-publications.com
Sodium butyrate (NaBu), a potent histone deacetylase inhibitor, modulates the expression
of a large number of genes. The purpose of this study was to determine whether this dietary …

New thiophene analogues of kenpaullone: synthesis and biological evaluation in breast cancer cells

L Brault, E Migianu, A Néguesque, E Battaglia… - European journal of …, 2005 - Elsevier
Thieno analogues of kenpaullone have been synthesized using an established method. We
investigated the effect of five structural analogues of kenpaullone on vincristine sensitive …

Bioaccumulation and subcellular partitioning of Cr (III) and Cr (VI) in the freshwater green alga Chlamydomonas reinhardtii

I Aharchaou, M Rosabal, F Liu, E Battaglia… - Aquatic Toxicology, 2017 - Elsevier
Chromium occurs in aquatic environments under two main redox forms, namely Cr(III) and
Cr(VI), with different geochemical and biochemical properties. Cr(VI) readily crosses …

Chromium hazard and risk assessment: New insights from a detailed speciation study in a standard test medium

…, G Cornelis, P Rousselle, E Battaglia… - Environmental …, 2018 - Wiley Online Library
Despite the consensus about the importance of chemical speciation in controlling the
bioavailability and ecotoxicity of trace elements, detailed speciation studies during laboratory …

Differential expression of CDC25 phosphatases splice variants in human breast cancer cells

H Albert, S Santos, E Battaglia, M Brito… - Clinical chemistry and …, 2011 - degruyter.com
Background: CDC25 phosphatases control cell cycle progression by activating cyclin
dependent kinases. The three CDC25 isoforms encoding genes are submitted to alternative …

Effects and bioaccumulation of Cr (III), Cr (VI) and their mixture in the freshwater mussel Corbicula fluminea

…, J Flayac, F Rodius, P Rousselle, M Beuret, E Battaglia… - Chemosphere, 2022 - Elsevier
Chromium has two main oxidation states, Cr(III) and Cr(VI), that can occur simultaneously in
natural waters. Current consensus holds that Cr(VI) is of high ecotoxicological concern, but …