User profiles for Erika Sasaki

Erika Sasaki

Central Institute for Experimental Animals
Verified email at ciea.or.jp
Cited by 7119

Generation of transgenic non-human primates with germline transmission

E Sasaki, H Suemizu, A Shimada, K Hanazawa… - Nature, 2009 - nature.com
The common marmoset (Callithrix jacchus) is increasingly attractive for use as a non-human
primate animal model in biomedical research. It has a relatively high reproduction rate for a …

Nongenetic method for purifying stem cell–derived cardiomyocytes

…, R Kaneda, M Murata, K Hidaka, T Morisaki, E Sasaki… - Nature …, 2010 - nature.com
Several applications of pluripotent stem cell (PSC)-derived cardiomyocytes require elimination
of undifferentiated cells. A major limitation for cardiomyocyte purification is the lack of …

Establishment of Novel Embryonic Stem Cell Lines Derived from the Common Marmoset (Callithrix jacchus)

E Sasaki, K Hanazawa, R Kurita, A Akatsuka… - Stem …, 2005 - academic.oup.com
The successful establishment of human embryonic stem cell (hESC) lines has inaugurated a
new era in regenerative medicine by facilitating the transplantation of differentiated ESCs to …

[PDF][PDF] Lineage-specific profiling delineates the emergence and progression of naive pluripotency in mammalian embryogenesis

…, R Loos, P Lombard, J Okahara, R Behr, E Sasaki… - Developmental cell, 2015 - cell.com
Naive pluripotency is manifest in the preimplantation mammalian embryo. Here we
determine transcriptome dynamics of mouse development from the eight-cell stage to …

The common marmoset as a novel animal model system for biomedical and neuroscience research applications

H Okano, K Hikishima, A Iriki, E Sasaki - Seminars in fetal and neonatal …, 2012 - Elsevier
The common marmoset (Callithrix jacchus), a small New World primate, has been attracting
much attention in the research field of biomedical science and neuroscience, based on its (i) …

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

…, P Gupta, JM Murithi, PA Moura, O Fuchs, E Sasaki… - Science, 2018 - science.org
Chemogenetic characterization through in vitro evolution combined with whole-genome
analysis can identify antimalarial drug targets and drug-resistance genes. We performed a …

Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset

…, Y Kurotaki, H Shinohara, H Okano, E Sasaki… - Science, 2020 - science.org
The neocortex has expanded during mammalian evolution. Overexpression studies in developing
mouse and ferret neocortex have implicated the human-specific gene ARHGAP11B in …

Common marmoset as a new model animal for neuroscience research and genome editing technology

N Kishi, K Sato, E Sasaki… - Development, growth & …, 2014 - Wiley Online Library
The common marmoset ( C allithrix jacchus) is a small N ew W orld primate; it originally
comes from the A tlantic coastal forests in northeastern B razil. It has been attracting much …

Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus

…, P Tomancak, F Matsuzaki, C Lebrand, E Sasaki… - Cerebral …, 2012 - academic.oup.com
Subventricular zone (SVZ) progenitors are a hallmark of the developing neocortex. Recent
studies described a novel type of SVZ progenitor that retains a basal process at mitosis, …

[HTML][HTML] Recent advances in the modeling of Alzheimer's disease

…, A Yoshiki, K Sato, W Kumita, E Sasaki… - Frontiers in …, 2022 - frontiersin.org
Since 1995, more than 100 transgenic (Tg) mouse models of Alzheimer’s disease (AD)
have been generated in which mutant amyloid precursor protein (APP) or APP/presenilin 1 (PS1) …