Hemophilia A is a bleeding disorder resulting from coagulation factor VIII (FVIII) deficiency.
Exogenously provided FVIII effectively reduces bleeding complications in patients with severe …

In hemophilia A, routine prophylaxis with exogenous factor VIII (FVIII) requires frequent
intravenous injections and can lead to the development of anti-FVIII alloantibodies (FVIII inhibitors…

Alport syndrome (AS) is a progressive hereditary renal disease that is characterized by
sensorineural hearing loss and ocular abnormalities. It is divided into three modes of inheritance, …

The Temperament and Character Inventory was translated into Japanese, and, to confirm
the psychometric properties of the inventory, three samples were recruited from a nonpatient …

Objectives. This study was designed to examine whether or not intramural delivery of ST638
(a specific tyrosine kinase inhibitor) with biodegradable stent can suppress the restenotic …

… Address correspondence to Eriko Tanaka, c/o Z Kitamura, Department of Sociocultural
Environmental Research, National Institute of Mental Health, 1-7-3 Kohnodai, Ichikawa, Chiba …

The extracellular adenosine triphosphate (ATP) concentration is highly elevated in the tumor
microenvironment (TME) and remains tightly regulated in normal tissues. Using phage …

Background Rituximab is the standard therapy for childhood-onset complicated frequently
relapsing or steroid-dependent nephrotic syndrome (FRNS/SDNS). However, most patients …

Creutzfeldt-Jakob disease causes progressive dementia and, eventually, death. The infectious
agent is thought to be proteinaceous scrapie particles. Prompt diagnosis is essential to …

To understand the genetics of steroid-sensitive nephrotic syndrome (SSNS), we conducted
a genome-wide association study in 987 childhood SSNS patients and 3,206 healthy …