User profiles for F. Luk

Franklin T Luk

Hong Kong Baptist University
Verified email at associate.hkbu.edu.hk
Cited by 4117

Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century

WH Lee, CY Loo, M Bebawy, F Luk… - Current …, 2013 - ingentaconnect.com
Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely
used in Southeast Asia, China and India in food preparation and for medicinal purposes. …

[HTML][HTML] The life and fate of mesenchymal stem cells

E Eggenhofer, F Luk, MH Dahlke… - Frontiers in …, 2014 - frontiersin.org
Mesenchymal stem cells (MSC) are present throughout the body and are thought to play a
role in tissue regeneration and control of inflammation. MSC can be easily expanded in vitro …

Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

R Callaghan, F Luk, M Bebawy - Drug Metabolism and Disposition, 2014 - ASPET
P-glycoprotein (P-gp) is a key player in the multidrug-resistant phenotype in cancer. The
protein confers resistance by mediating the ATP-dependent efflux of an astonishing array of …

Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells

SFH de Witte, F Luk, JM Sierra Parraga, M Gargesha… - stem cells, 2018 - academic.oup.com
… 4F), demonstrating that phagocytosis of ucMSC by monocytes is an active process. … 5F).
However, in contrast to monocytes that phagocytosed ucMSC, monocytes cultured in ucMSC …

The solution of singular-value and symmetric eigenvalue problems on multiprocessor arrays

RP Brent, FT Luk - SIAM Journal on Scientific and Statistical Computing, 1985 - SIAM
… His method is essentially the serial Jacobi procedure for finding an eigenvalue decomposition
of the matrix ATA, and has been used by Luk [20] on the ILLIACIV computer. We also …

Computation of the singular value decomposition using mesh-connected processors

RP Brent, FT Luk, C Van Loan - 1982 - ecommons.cornell.edu
… matrices detailedin Forsytheand Henrici G and show howitcan beimplementedonasystoic
array,Thearrayisverysimilartothe oneproposedin Brentand Luk冈thatuses O(n)processors to …

[HTML][HTML] Determinants of quantitative optical coherence tomography angiography metrics in patients with diabetes

FY Tang, DS Ng, A Lam, F Luk, R Wong, C Chan… - Scientific reports, 2017 - nature.com
Early microvascular damage in diabetes (eg capillary nonperfusion and ischemia) can now
be assessed and quantified with optical coherence tomography-angiography (OCT-A). The …

Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB–driven inflammation and atherosclerosis

K Li, D Ching, FS Luk, RL Raffai - Circulation research, 2015 - Am Heart Assoc
… Representative histograms (E) and quantification (F) of p65 phosphorylation in 4-week-old
WT and Apoe –/– macrophages before (Ctrl) or after LPS stimulation for 15 minutes (100 ng/…

[PDF][PDF] A block Lanczos method for computing the singular values and corresponding singular vectors of a matrix

GH Golub, FT Luk, ML Overton - ACM Transactions on Mathematical …, 1981 - dl.acm.org
We present a block Lanczos method for computing the greatest singular values and
associated vectors of a large and sparse matrix, say A. Our algorithm does not transform A but …

Inactivated mesenchymal stem cells maintain immunomodulatory capacity

F Luk, SFH De Witte, SS Korevaar… - Stem cells and …, 2016 - liebertpub.com
… (f) FACS plots of cell surface markers on control MSC (solid line and percentage top line)
and HI-MSC (dotted line and percentage bottom line) compared to the unstained control (gray) …