User profiles for G. Cherala

Ganesh Cherala

BioMarin Pharmaceutical Inc.
Verified email at bmrn.com
Cited by 1438

Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review

AB Edelman, G Cherala, FZ Stanczyk - Contraception, 2010 - Elsevier
The effect of obesity on drug metabolism and pharmacokinetics is poorly understood, and
this is particularly true in regard to contraceptive steroids. This article will review the known …

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

JJ Alumkal, R Slottke, J Schwartzman, G Cherala… - Investigational new …, 2015 - Springer
Introduction Diets high in cruciferous vegetables are associated with lower risk of incidence
of prostate cancer, including aggressive forms of this disease. Human intervention studies …

Impact of obesity on oral contraceptive pharmacokinetics and hypothalamic–pituitary–ovarian activity

AB Edelman, NE Carlson, G Cherala, MY Munar… - Contraception, 2009 - Elsevier
BACKGROUND: This study was conducted to determine whether increased body mass index
(BMI) affects oral contraceptive (OC) pharmacokinetics and suppression of hypothalamic–…

Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry

DR Koop, LA Bleyle, M Munar, G Cherala… - … of Chromatography B, 2013 - Elsevier
… Precipitated protein was removed by centrifugation for 5 min at 14,000 × g. The supernatant
was transferred to an autosampler vial and analyzed by LC–MS/MS as described below. …

Impact of obesity on the pharmacokinetics of levonorgestrel-based emergency contraception: single and double dosing

AB Edelman, G Cherala, SW Blue, DW Erikson… - Contraception, 2016 - Elsevier
… Edelman a , Ganesh Cherala a b 1 , Steven W. Blue c , David W. Erikson c , Jeffrey T. … G.
Cherala, S Blue, and D Erikson have nothing to disclose. …

[PDF][PDF] Cytosolic sulfotransferases

D Nimmagadda, G Cherala, S Ghatta - 2006 - academia.edu
Sulfoconjugation (Sulfation or Sulfonation) is an important reaction in the phase II
biotransformation of a wide number of endogenous and foreign chemicals, including: drugs, toxic …

Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters

…, GH Marracci, MY Munar, G Cherala… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Lipoic acid is a natural anti-oxidant available as an oral supplement from a number of different
manufacturers. Lipoic acid administered subcutaneously is an effective therapy for murine …

Association of platelet responsiveness with clopidogrel metabolism: role of compliance in the assessment of “resistance”

V Serebruany, G Cherala, C Williams, S Surigin… - American heart …, 2009 - Elsevier
… The blood-citrate mixture was centrifuged at 1,200 g for 2.5 minutes. The resulting platelet-rich
plasma was kept at room temperature for use within 1 hour. The platelet count was …

[HTML][HTML] Double dosing levonorgestrel-based emergency contraception for individuals with obesity: a randomized controlled trial

…, JD Hennebold, K Bond, JY Lim, G Cherala… - Obstetrics & …, 2022 - journals.lww.com
… Ganesh Cherala was involved in this study as a private consultant. He is employed by
Gilead Sciences, which was not involved in this research. The other authors did not report any …

Prolonged monitoring of ethinyl estradiol and levonorgestrel levels confirms an altered pharmacokinetic profile in obese oral contraceptives users

AB Edelman, G Cherala, MY Munar, B DuBois… - Contraception, 2013 - Elsevier
BACKGROUND: Pharmacokinetic (PK) parameters based on short sampling times (48 h or
less) may contain inaccuracies due to their dependency on extrapolated values. This study …