… /H2O2 results in the formation of mainly C to T, G to T, and G to C substitutions in the iron
system, with C to T and G to T substitutions and CC to TT tandem double transitions in the …

… The blood was centrifuged at 1500 g for 10 min in a swing-out rotor, and 100 μl supernatant
plasma was removed and used to measure plasma concentrations of CPT-11 and SN-38. …

Imatinib mesylate is a selective tyrosine kinase inhibitor that is successfully used in the
treatment of Philadelphia-positive chronic and acute leukaemia's, and gastrointestinal stromal …

Objective Our objective was to explore the relationships between imatinib pharmacokinetics
and 9 allelic variants in 7 genes coding for adenosine triphosphate‐binding cassette …

Nanotechnology is being exploited now in different fields of analytical chemistry: Single cell
analysis; in chip/micro machined devices; hyphenated technology and sampling techniques. …

The shape of a normal human red blood cell (RBC) is well known: under resting conditions it
is that of a biconcave discocyte. However, RBCs can easily undergo transformation to other …

Imatinib and AMN107 are protein tyrosine kinase inhibitors which reduce KIT autophosphorylation
with similar potency. This report describes the cellular uptake of these compounds in …

… Tumour and liver tissues were homogenised in 2 ml acetonitrile (Pro 200 homogenizer, Pro
Scientific, CT, USA) and centrifuged at 2500 g. Melphalan was measured in the supernatant …

Background Up to 66% of patients show local pulmonary disease progression after pulmonary
metastasectomy. Regional treatment with isolated lung perfusion (ILuP) may improve …

Background Isolated hepatic perfusion for irresectable metastases confined to the liver has
reported response rates of 50% to 75%. Magnitude, costs, and nonrepeatability of the …