User profiles for G. Minotti
Giorgio MinottiProfessore Ordinario di Farmacologia, Universitą Campus Bio-Medico di Roma Verified email at unicampus.it Cited by 18117 |
Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
… in G 1 to S transition. Whereas this mechanism has been proposed to contribute to G 1 arrest
… might protect cells from DOX because the G 1 block facilitates DNA repair before the cells …
… might protect cells from DOX because the G 1 block facilitates DNA repair before the cells …
Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement
…, G Curigliano, JD Mitchell, G Minotti… - European heart …, 2022 - academic.oup.com
The discipline of Cardio-Oncology has seen tremendous growth over the past decade. It is
devoted to the cardiovascular (CV) care of the cancer patient, especially to the mitigation and …
devoted to the cardiovascular (CV) care of the cancer patient, especially to the mitigation and …
[HTML][HTML] Anthracycline cardiotoxicity: from bench to bedside
…, EH Herman, SE Lipshultz, G Minotti… - Journal of clinical …, 2008 - ncbi.nlm.nih.gov
Anthracyclines remain among the most widely prescribed and effective anticancer agents.
Unfortunately, life-threatening cardiotoxicity continues to compromise their usefulness. …
Unfortunately, life-threatening cardiotoxicity continues to compromise their usefulness. …
[HTML][HTML] The requirement for iron (III) in the initiation of lipid peroxidation by iron (II) and hydrogen peroxide.
… Catalase was separated from the antioxidant thymol by gel chromatography on Sephadex
G-25. Following chromatography the enzyme activity was measured by the method of Beers …
G-25. Following chromatography the enzyme activity was measured by the method of Beers …
In Vivo Formation of 8-Epi-Prostaglandin F2α Is Increased in Hypercholesterolemia
…, P Alessandrini, A Mezzetti, G Minotti… - … , and vascular biology, 1997 - Am Heart Assoc
F 2 -isoprostanes are bioactive prostaglandin (PG) -like compounds that are produced from
arachidonic acid through a nonenzymatic process of lipid peroxidation catalyzed by oxygen …
arachidonic acid through a nonenzymatic process of lipid peroxidation catalyzed by oxygen …
Role of iron in anthracycline cardiotoxicity: new tunes for an old song?
… Minotti, G. (1989) Adriamycin dependent release of iron from microsomal membranes. Arch.
… Minotti, G. (1990) NADPH and adriamycin dependent microsomal release of iron and lipid …
… Minotti, G. (1990) NADPH and adriamycin dependent microsomal release of iron and lipid …
An investigation into thee mechanism of citrate FE2+-dependent lipid peroxidation
… Gel-chromatography on Sephadex G-25, equilibrated with 0.3 M NaC1, pH 7.0, was used to
… Minotti, G.; Aust, SD The requirement for ferric in the initiation of lipid peroxidation by ferrous …
… Minotti, G.; Aust, SD The requirement for ferric in the initiation of lipid peroxidation by ferrous …
The role of iron in the initiation of lipid peroxidation
… Data taken in part from Minotti and Aust [16]. Incubations contained microsomai phospholipid
llposomes (1 ~mot lipid phosphate/ml), 0.33 mM xanthine and ADP-Fe )ק (0.11 mM ADP/…
llposomes (1 ~mot lipid phosphate/ml), 0.33 mM xanthine and ADP-Fe )ק (0.11 mM ADP/…
Redox cycling of iron and lipid peroxidation
… NaCl was chromatographed on Chelex-100 to remove contaminating metals, and catalase
was chromatographed on Sephadex G-25 to remove the antioxidant thymol and other …
was chromatographed on Sephadex G-25 to remove the antioxidant thymol and other …
Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated …
Abstract Changes in iron homeostasis have been implicated in cardiotoxicity induced by the
anticancer anthracycline doxorubicin (DOX). Certain products of DOX metabolism, like the …
anticancer anthracycline doxorubicin (DOX). Certain products of DOX metabolism, like the …