[PDF][PDF] Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure

P Merlet, H Valette, JL Dubois-Randé… - Journal of Nuclear …, 1992 - Soc Nuclear Med
… (H/M) activity ratio was then computed to quantify cardiac MIBG uptake. For each patient, the
H/M value was taken as the averageof measurementsperformedover his scintigraphicimage…

Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study

…, A Gambardella, B Steinborn, A Hufnagel, H Valette… - Brain, 2006 - academic.oup.com
Nicotinic acetylcholine receptors (nAChRs) are involved in a familial form of frontal lobe
epilepsy, autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). In several ADNFLE …

Positron emission tomography with 11C CGP-12177 to assess beta-adrenergic receptor concentration in idiopathic dilated cardiomyopathy.

…, A Syrota, E Angevin, B Maziere, C Crouzel, H Valette… - Circulation, 1993 - Am Heart Assoc
BACKGROUND Positron emission tomography (PET) with 11C-labeled CGP-12177 (CGP)
has been shown to have the potential to noninvasively measure beta-adrenergic receptor …

Metabolism and quantification of [18F] DPA-714, a new TSPO positron emission tomography radioligand

…, F Dollé, M Kassiou, M Bottlaender, H Valette - Drug Metabolism and …, 2013 - ASPET
… The cartridge was then sequentially washed with 1 ml of H 2 O (fraction F2), then with a
CH 3 CN/H 2 O solution (fraction F3). Several concentrations of CH 3 CN (15 concentrations …

Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography …

F Dollé, L Dolci, H Valette, F Hinnen… - Journal of medicinal …, 1999 - ACS Publications
… In vitro, the fluoro derivative of A-85380 (2-fluoro-3-[(S)-2-azetidinylmethoxy]pyridine or
FA-85380) competitively displaced [ 3 H]cytisine or [ 3 H]epibatidine with K i values of 48 and 46 …

Beta-blocking agent for treatment ofInfantile hemangioma

M Bigorre, AK Van Kien, H Valette - Plastic and reconstructive …, 2009 - journals.lww.com
For function-and life-threatening hemangiomas, the first-line medical treatment is corticosteroid,
followed by vincristine or interferon. 1–3 Corticosteroid results in regression in 40 percent…

In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET

…, M Ottaviani, F Dollé, A Syrota, H Valette - Journal of Nuclear …, 2005 - Soc Nuclear Med
… The thalamus was excluded from this analysis, because no washout phase could be
observed during the 4 h of the experiment in most subjects; therefore, the 4-h DV estimates could …

Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide

…, A Dubois, F Dollé, JM Scherrmann, H Valette… - The AAPS journal, 2013 - Springer
… This distribution volume was used to check BBB integrity and enabled us to correct [ 3 H]GLB
brain activity based on the vascular content. The apparent distribution volume of [ 3 H]GLB (…

[11C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: Preclinical characterisation in nonhuman primate

W Saba, H Valette, MA Peyronneau, Y Bramoullé… - Synapse, 2010 - Wiley Online Library
[ 11 C]SL‐25.1188 [(S)‐5‐methoxymethyl‐3‐[6‐(4,4,4‐trifluorobutoxy)‐benzo[d]isoxazol‐3‐yl]‐oxazolidin‐2‐one],
an oxazolidinone derivative, was characterized in baboons as a …

Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers

M Bottlaender, H Valette, D Roumenov… - Journal of Nuclear …, 2003 - Soc Nuclear Med
… Emission scans (1 min per step) were acquired over 2 h. Venous blood samples were taken
up to 2 h after injection of the radiotracer. Urine was freely collected up to 2 h after injection …