The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil

HY Ku, HJ Ahn, KA Seo, H Kim, M Oh, SK Bae… - Drug Metabolism and …, 2008 - ASPET
The role of the genetically polymorphic CYP3A5 in the metabolism of CYP3A substrates is
unclear. We investigated the contributions of the CYP3A4 and CYP3A5 isoforms to the …

The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity

KA Seo, H Kim, HY Ku, HJ Ahn, SJ Park, SK Bae… - Chemico-biological …, 2008 - Elsevier
Monoterpenes are found in the volatile essence of flowers, plants oils, and herbal medicines.
Some are commonly used as food additives and fragrance components, and many are …

Identification and characterization of potent CYP2B6 inhibitors in Woohwangcheongsimwon suspension, an herbal preparation used in the treatment and prevention …

H Kim, KB Kim, HY Ku, SJ Park, H Choi, JK Moon… - Drug metabolism and …, 2008 - ASPET
Woohwangcheongsimwon is a traditional medicine for treating hypertension, arteriosclerosis,
coma, and stroke in China and Korea. To assess potential interactions of herb and drug …

Liquid chromatography/tandem mass spectrometry method for the simultaneous determination of vardenafil and its major metabolite, N-desethylvardenafil, in human …

HY Ku, JH Shon, KH Liu, JG Shin, SK Bae - Journal of Chromatography B, 2009 - Elsevier
A rapid and sensitive LC–MS/MS method for the determination of vardenafil and its major
metabolite, N-desethylvardenafil, in human plasma using sildenafil as an internal standard …

The disposition of three phosphodiesterase type 5 inhibitors, vardenafil, sildenafil, and udenafil, is differently influenced by the CYP3A5 genotype

JH Shon, HY Ku, SY Bae, MK Oh, CW Yeo… - Pharmacogenetics …, 2011 - journals.lww.com
Objectives This study was conducted to compare the effect of CYP3A5* 3 genotype on the
disposition of three phosphodiesterase type 5 inhibitors (PDE5Is), vardenafil, sildenafil, and …

Inhibition of Drug-metabolizing Enzyme and Drug Transporter by Major Components of Phellodendri cortex

HY Ku, H Kim, JH Shon, KH Liu - Journal of Marine Bioscience and …, 2006 - koreascience.kr
We evaluated the potential of major components of Phellodendri cortex to inhibit the
activities of CYP2D6 and p-glycoprotein. The abilities of berberine, palmatine, limonin, and …

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans

SJ Lee, SS Lee, HJ Jung, HS Kim, SJ Park… - Drug metabolism and …, 2009 - ASPET
Our objectives were to identify CYP2D6 genetic polymorphisms in a Korean population, to
compare the allele frequencies with those of other ethnic groups, and to evaluate variant-…

[CITATION][C] Busan National University

X Entertainment - dbpia.co.kr
List of Artist Page 1 List of Artist Kang, Bum Kyu Kang, Soo Doul Kang, Yun Geuk Kang, Cheol
Gu Kang, Hyun Ock Kang, Hong Gue Go, Jung Wook Kong, Ok Hee Kwak, No Jun Kwon, …

[BOOK][B] Experimental measurement of nonlinear energy transfer on the Tokamak Fusion Test Reactor

JS Kim - 1996 - search.proquest.com
… And finally my deepest thanks to my wife, Hei-Young, whose support has been invaluable.
This work was … That is, fluctuations satisfy the condition plasma «ku where do plasma …

[PDF][PDF] PROFESSIONAL CARDS. GEO. O. GRATTAN, ATTOBNBT-AT-LAW, HAOiaoaBtTM. TA. WOfflc* Routlk Sid* of Ooart-Houn Bqatr*.

WMB COMPTON, J HAY - core.ac.uk
WJJillliinicr&fe, EAST MARKET ST. H< arrisoiit)\xrgiy" Va. The attention of the trade is
respectfully called to our stock of GUtOO ERIK S. consisting of Sugars. Coffers. Teas and Rice, …