Determination of the metabolites of the new designer drugs bk-MBDB and bk-MDEA in human urine

K Zaitsu, M Katagi, HT Kamata, T Kamata… - Forensic science …, 2009 - Elsevier
This is the first report on identifying the specific metabolites of the new designer drugs 2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one
(bk-MBDB) and 2-ethylamino-1-(3,4-…

Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N, N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites

T Kamata, M Katagi, HT Kamata, A Miki, N Shima… - Drug metabolism and …, 2006 - ASPET
The urinary metabolites of 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) in humans
have been investigated by analyzing urine specimens from its users. For the unequivocal …

Discrimination and identification of regioisomeric β-keto analogues of 3, 4-methylenedioxyamphetamines by gas chromatography-mass spectrometry

K Zaitsu, M Katagi, HT Kamata, A Miki… - Forensic Toxicology, 2008 - Springer
Very recently, β-keto derivatives of 3,4-methylenedioxyamphetamines (MDAs) have
appeared on the illicit drug market. In the present study, we synthesized three isomers of β-keto …

Simultaneous analysis of new designer drug, methylone, and its metabolites in urine by gas chromatography-mass spectrometry and liquid chromatography …

HT Kamata, N Shima, K Zaitsu, T Kamata… - Japanese Journal of …, 2007 - jstage.jst.go.jp
Introduction Methylone [2 methylamino 1(3, 4 methylenedioxyphenyl) propan 1 one],
the b keto analogue of 3, 4 methylenedioxymethamphetamine (MDMA), increases the …

Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites

…, M Katagi, H Kamata, S Matsuta, K Sasaki, T Kamata… - Forensic …, 2014 - Springer
Urinary metabolites of α-pyrrolidinovalerophenone (α-PVP) in humans were investigated by
analyzing urine specimens obtained from abusers. Unambiguous identification and …

Incorporation of zolpidem into hair and its distribution after a single administration

N Shima, K Sasaki, T Kamata, S Matsuta… - Drug Metabolism and …, 2017 - ASPET
To obtain fundamental information on the drug incorporation into hair, time-course changes
in drug distribution along single-strand hair were observed after a single oral administration …

Metabolism of the designer drug α-pyrrolidinobutiophenone (α-PBP) in humans: identification and quantification of the phase I metabolites in urine

…, H Kakehashi, S Nakano, K Sasaki, T Kamata… - Forensic Science …, 2015 - Elsevier
… In contrast, 4′-hydroxy metabolites of α-PBP couldn’t be detected in the present study.
Based on these findings, a considerable interspecies variation could exist in the phase I …

Effects of lipophilicity and functional groups of synthetic cannabinoids on their blood concentrations and urinary excretion

…, S Matsuta, K Sasaki, H Kamata, T Kamata… - Forensic science …, 2020 - Elsevier
The influence of lipophilicity and functional groups of synthetic cannabinoids (SCs) on their
blood concentrations and urinary excretion has been studied by analyzing blood and urine …

Incorporation of zolpidem and methoxyphenamine into white hair strands after single administrations: Influence of hair pigmentation on drug incorporation

N Shima, A Nitta, T Kamata, K Sasaki, S Matsuta… - Forensic science …, 2019 - Elsevier
In order to investigate the influence of pigmentation on the incorporation of drugs into hair,
time-course changes in drug distribution along non-pigmented (white) hairs as well as …

Urinary excretion and metabolism of the α-pyrrolidinophenone designer drug 1-phenyl-2-(pyrrolidin-1-yl) octan-1-one (PV9) in humans

…, H Kamata, S Nakano, K Sasaki, T Kamata… - Forensic …, 2015 - Springer
Phenyl-2-(pyrrolidin-1-yl)octan-1-one (PV9) and 16 metabolites, including diastereomers and
conjugates, were identified or tentatively detected in human urine by gas chromatography–…