Sulfotransferase molecular biology: cDNAs and genes

RM Weinshilboum, DM Otterness, IA Aksoy… - The FASEB …, 1997 - Wiley Online Library
Sulfotransferase (ST) enzymes cata‐lyze the sulfate conjugation of many hormones, neu‐rotransmitters,
drugs, and xenobiotic compounds. These reactions result in enhanced renal …

DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication.

KS Campbell, KP Mullane, IA Aksoy… - Genes & …, 1997 - genesdev.cshlp.org
The amino-terminal domain of SV40 large tumor antigen (TAg) is required for efficient viral
DNA replication. However, the biochemical activity associated with this domain has remained …

Human liver estrogen sulfotransferase: identification by cDNA cloning and expression

IA Aksoy, TC Wood, R Weinshilboum - Biochemical and biophysical …, 1994 - Elsevier
Aksoy, Thomas C. Wood and Richard Weinshilboum* … Saime Aksoy and Diane
Otterness for their assistance and advice, and Dr. Eric Wieben for reading the manuscript. …

Human jejunal estrogen sulfotransferase and dehydroepiandrosterone sulfotransferase: immunochemical characterization of individual variation.

C Her, C Szumlanski, IA Aksoy… - Drug Metabolism and …, 1996 - ASPET
Sulfate conjugation is an important metabolic pathway for many drugs, xenobiotic compounds,
and steroid hormones. Human tissues express five cytoplasmic sulfotransferase (ST) …

Spinal accessory neuropathy associated with deep tissue massage: a case report

IA Aksoy, SL Schrader, MS Ali, JA Borovansky… - Archives of physical …, 2009 - Elsevier
Aksoy IA, Schrader SL, Ali MS, Borovansky JA, Ross MA. Spinal accessory neuropathy
associated with deep tissue massage: a case report. Spinal accessory neuropathy (SAN) causes …

[PDF][PDF] Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA.

R Honchel, IA Aksoy, C Szumlanski, TC Wood… - Molecular …, 1993 - Citeseer
Thiopurine methyltransferase(TPMT) catalyzes the S-methyla-tion of thiopurine drugs such
as 6-mercaptopurine. Levels of TPMT activity in human tissue are controlled by a common …

Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization

TC Wood, IA Aksoy, S Aksoy… - … and biophysical research …, 1994 - Elsevier
The sulfate conjugation of phenolic biogenic amines in humans is catalyzed by the thermolabile
(TL) form of phenol sulfotransferase (PSI). As a first step toward cloning a cDNA for TL …

D-3-Deoxy-3-substitutedmyo-inositol analogues as inhibitors of cell growth

G Powis, IA Aksoy, DC Melder, S Aksoy… - Cancer chemotherapy …, 1991 - Springer
A number of unnaturald-3-deoxy-3-substitutedmyo-inositols were synthesized and their
effects on the growth of wild-type NIH 3T3 cells and oncogenetransformed NIH 3T3 cells were …

Human liver dehydroepiandrosterone sulfotransferase: nature and extent of individual variation

IA Aksoy, V Sochorová… - Clinical Pharmacology & …, 1993 - Wiley Online Library
… One important reason is that, unlike the PSTs, DHEA ST is not expressed in human blood
elements (Otterness DM, Aksoy IA, Weinshilboum RM, unpublished observation), even though …

[PDF][PDF] Cholesterol sulfation in human liver. Catalysis by dehydroepiandrosterone sulfotransferase.

IA Aksoy, DM Otterness, RM Weinshilboum - Drug metabolism and …, 1993 - Citeseer
Cholesterol can undergo sulfate conjugation to form cholesterol 3-sulfate. Our experiments
were performed to determine whether hu-man liver cytosol could catalyze the sulfatlon of …