It is generally recognized that drug discovery and development are very time and resources
consuming processes. There is an ever growing effort to apply computational power to the …

Purpose Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a naturally occurring polyphenol
with a broad range of possible health benefits, including anti-cancer activity. However, the …

Bioinformatics, in its broad sense, involves application of computer processes to solve biological
problems. A wide range of computational tools are needed to effectively and efficiently …

Standardized green tea extract was evaluated for exposure and toxicity in Beagle dogs
following oral dosing by capsules. The main component (−)-epigallocatechin gallate (EGCG) …

Resveratrol (trans‐resveratrol, trans‐3,5,4′‐trihydroxystilbene) is a naturally occurring
stilbene analogue found in high concentrations in red wine. There is considerable research …

An analytical approach for the determination of trans-resveratrol (3,5,4′-trihydroxy-trans-stilbene)
and its glucuronide and sulfate conjugates in dog plasma by LC–MS/MS (without …

Purpose: Naturally occurring flavonoids such as quercetin and genistein possess cancer
chemopreventive properties in experimental models. However, adverse effects such as their …

… In electrophysiological studies using hippocampal slices, D-23129 also behaved differently
from flupirtine (Yonekawa, WD, Kapetanovic, IM and Kupferberg, HJ, unpublished results). …

… Ka~etanovii IM. Kupferberg HJ: Inhibition of microsomal phenobarbital metabolism by val…
Kapetanovii IM, Kupferberg HJ: Stable isotope methodology and gas chromatography-mass …

SHetA2 is a heteroarotinoid that has shown selective inhibition of cancer cell growth and an
induction of apoptosis without activation of nuclear retinoic acid receptors. In the rat study, …