Design of liposomes as drug delivery system for therapeutic applications
D Guimarães, A Cavaco-Paulo, E Nogueira - International journal of …, 2021 - Elsevier
Liposomes are spherical vesicles consisting of one or more concentric phospholipid bilayers
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent …
enclosing an aqueous core. Being both nontoxic and biodegradable, liposomes represent …
Metabolic regulation is important for spermatogenesis
Male factor infertility is increasing in developed countries, and several factors linked to
lifestyle have been shown to negatively affect spermatogenesis. Sertoli cells are pivotal to …
lifestyle have been shown to negatively affect spermatogenesis. Sertoli cells are pivotal to …
[HTML][HTML] A brief multi-disciplinary review on antimicrobial resistance in medicine and its linkage to the global environmental microbiota
The discovery and introduction of antimicrobial agents to clinical medicine was one of the
greatest medical triumphs of the 20th century that revolutionized the treatment of bacterial …
greatest medical triumphs of the 20th century that revolutionized the treatment of bacterial …
[HTML][HTML] The IASLC lung cancer staging project: proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung …
…, M Okumura, E Blackstone, FA Cavaco… - Journal of Thoracic …, 2016 - Elsevier
The IASLC Staging and Prognostic Factors Committee has collected a new database of
94,708 cases donated from 35 sources in 16 countries around the globe. This has now been …
94,708 cases donated from 35 sources in 16 countries around the globe. This has now been …
Decolorization and Detoxification of Textile Dyes with a Laccase from Trametes hirsuta
…, S Costa, KH Robra, A Cavaco-Paulo… - Applied and …, 2000 - Am Soc Microbiol
Trametes hirsuta and a purified laccase from this organism were able to degrade triarylmethane,
indigoid, azo, and anthraquinonic dyes. Initial decolorization velocities depended on …
indigoid, azo, and anthraquinonic dyes. Initial decolorization velocities depended on …
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome
…, B Robinson, RJ Zarbo, BM Cavaco… - Nature …, 2002 - nature.com
We report here the identification of a gene associated with the hyperparathyroidism–jaw
tumor (HPT–JT) syndrome. A single locus associated with HPT–JT (HRPT2) was previously …
tumor (HPT–JT) syndrome. A single locus associated with HPT–JT (HRPT2) was previously …
qnrD, a Novel Gene Conferring Transferable Quinolone Resistance in Salmonella enterica Serovar Kentucky and Bovismorbificans Strains of Human Origin
In a previous study, four Salmonella isolates from humans in the Henan province of China
showed reduced susceptibility to ciprofloxacin (MIC, 0.125 to 0.25 μg/ml) but were susceptible …
showed reduced susceptibility to ciprofloxacin (MIC, 0.125 to 0.25 μg/ml) but were susceptible …
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas
…, C Lobo, MJ Martins, M Moura, B Cavaco… - The Journal of …, 2014 - academic.oup.com
Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-derived
thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers. …
thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers. …
PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens
Background Antibiotic resistance is a major health problem, as drugs that were once highly
effective no longer cure bacterial infections. WGS has previously been shown to be an …
effective no longer cure bacterial infections. WGS has previously been shown to be an …
Biodegradable materials based on silk fibroin and keratin
A Vasconcelos, G Freddi, A Cavaco-Paulo - Biomacromolecules, 2008 - ACS Publications
Wool and silk were dissolved and used for the preparation of blended films. Two systems
are proposed: (1) blend films of silk fibroin and keratin aqueous solutions and (2) silk fibroin …
are proposed: (1) blend films of silk fibroin and keratin aqueous solutions and (2) silk fibroin …