In silico and in vitro screening for inhibition of cytochrome P450 CYP3A4 by comedications commonly used by patients with cancer

JD Marechal, J Yu, S Brown, I Kapelioukh… - Drug metabolism and …, 2006 - ASPET
Cytochrome P450 3A4 (CYP3A4) is the major enzyme responsible for phase I drug metabolism
of many anticancer agents. It is also a major route for metabolism of many drugs used by …

Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis.

SV Zaitsev, IB Appelskog, IL Kapelioukh, SN Yang… - Diabetes, 2001 - Am Diabetes Assoc
Imidazoline compounds have been considered for the treatment of type 2 diabetes. We
have now investigated the effects of imidazolines on interleukin (IL)-1beta-induced beta-cell …

Calcium has a permissive role in interleukin-1β-induced c-jun N-terminal kinase activation in insulin-secreting cells

J Størling, SV Zaitsev, IL Kapelioukh, AE Karlsen… - …, 2005 - academic.oup.com
The c-jun N-terminal kinase (JNK) signaling pathway mediates IL-1β-induced apoptosis in
insulin-secreting cells, a mechanism relevant to the destruction of pancreatic β-cells in type 1 …

On-line monitoring of apoptosis in insulin-secreting cells

…, B Leibiger, IB Leibiger, M Turunen, IL Kapelioukh… - Diabetes, 2003 - Am Diabetes Assoc
Apoptosis was monitored in intact insulin-producing cells both with microfluorometry and
with two-photon laser scanning microscopy (TPLSM), using a fluorescent protein based on …

Rainbow tags: a visual tag system for recombinant protein expression and purification

RD Finn, I Kapelioukh, MJI Paine - Biotechniques, 2005 - Future Science
Visualization systems for tracking proteins are standard experimental tools in most areas of
biological research apart from protein purification. Here, we have sought to plug this gap by …

PAT Fi

HC Kelman, E Said, Y Harkabi, A Kapeliouk, W Khalidi… - cambridge.org
This is the key volume in a series of reports on the archaeological excavations at the medieval
site of Nishapur in northeastern Iran. It is a copiously illustrated report of the Metropolitan …

[BOOK][B] La grande Europe?

C Delsol, H Świda-Ziemba - 1994 - researchgate.net
La mémoire a pris de plus en plus d'empire dans nos sociétés. Pourtant, le singulier vertige
de la remémoration ne revêt pas partout la même signification. Si la rumination du passé à …

[BOOK][B] Cytokine-induced beta-cell apoptosis and its regulation by SOCS-1 and imidazoline compounds

I Zaitseva - 2014 - search.proquest.com
A selective destruction of pancreatic β-cells as a consequence of inflammation in the islets
of Langerhans is a feature of type 1 diabetes. Pro-inflammatory cytokines secreted by T …

Opinion: Thought control in the USA: The case of the Middle East

N Chomsky - 1986 - Taylor & Francis
… Lauro, but not the Israeli bombing near Tunis on 1 October, killing 55 Palestinians and 20
Tunisians according to the graphic report from the scene by Israeli journalist Annon Kapeliouk. …

[BOOK][B] Assessment of pancreatic islet cell function and survival

M Köhler - 2015 - openarchive.ki.se
Function and survival of pancreatic islet insulin-producing beta-cells (β-cells) and
glucagonproducing alpha-cells (α-cells) were studied, and methods for this purpose were developed …