Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated …

DA Wink, JF Darbyshire, RW Nims… - Chemical research in …, 1993 - ACS Publications
A recent discovery in mammalian biology has been the important physiological role that
nitric oxide plays in blood pressure regulation, neurotransmission, macrophage-in-duced …

Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of …

DA Wink, RW Nims, JF Darbyshire… - Chemical research in …, 1994 - ACS Publications
Asno=(6±2) X 106 M™ 2 s-1, a value identical to that forthe formation of reactive intermediates
in the autoxidation of NO. Competition studies performed with a variety of aminoacids, …

Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent

DA Wink, Y Osawa, JF Darbyshire, CR Jones… - Archives of biochemistry …, 1993 - Elsevier
The effect of nitric oxide (NO) on cytochrome P450-mediated benzyloxyresorufin and
ethoxyresorufin O-dealkylase activity of rat hepatic postmitochondrial (S-9) or microsomal …

Colorimetric methods for the determination of nitric oxide concentration in neutral aqueous solutions

RW Nims, JF Darbyshire, JE Saavedra… - Methods, 1995 - Elsevier
Two convenient colorimetric methods are described for the determination of nitric oxide (NO)
concentration in neutral aqueous solutions. Both techniques take advantage of the fact that …

Functional diversity amongst soil protozoa

MM Coûteaux, JF Darbyshire - Applied Soil Ecology, 1998 - Elsevier
Organismal and functional diversity of soil protozoa are reviewed and the importance of
protozoa in soil metabolism is discussed. Existing methods of determining protozoan organismal …

[BOOK][B] Soil protozoa

JF Darbyshire, JF Darbyshire - 1994 - scholar.archive.org
The Com− position and Distribution of the Pretozoan Fauna in the Seil” 以来, 約 70 年ぶ りの
土壌原生動物の 生態 に関す るテ キ ス トで ある. こ れまで 土壌微生物生態学の 研究対象は, 主…

Bacteria and protozoa in the rhizosphere

JF Darbyshire, MP Greaves - Pesticide science, 1973 - Wiley Online Library
The origin and a modern interpretation of the term “rhizosphere”, the zone of soil close to
plant roots, are discussed with special reference to soil bacteria and protozoa. The physical, …

Discovery of 3-Methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an Orally Bioavailable Dopamine D4 Agonist for the …

…, KC Marsh, R Martin, JF Darbyshire… - Journal of medicinal …, 2006 - ACS Publications
The goal of this study was to identify a structurally distinct D 4 -selective agonist with superior
oral bioavailability to our first-generation clinical candidate 1a (ABT-724) for the potential …

Soil fungi as food for giant amoebae

KM Old, JF Darbyshire - Soil Biology and Biochemistry, 1978 - Elsevier
Feeding trials were carried out to assess the ability of a giant vampyrellid soil amoeba to
attack and lyse spores of fungi. Of 24 species of fungi studies, 15 were perforated in the same …

Image analysis and three‐dimensional modelling of pores in soil aggregates

…, GW Horgan, JF Darbyshire - Journal of Soil Science, 1991 - Wiley Online Library
Three cross‐sections of soil aggregates (2–5 mm diameter) were digitized at 5 μm resolution
from montages (× 100) of scanning electron micrographs to produce binary images …