25-Hydroxyvitamin D3 26, 23-lactone: a new in vivo metabolite of vitamin D

JK Wichmann, HF DeLuca, HK Schnoes, RL Horst… - Biochemistry, 1979 - ACS Publications
Joseph K. Wichmann, Hector F. DeFuca,* Heinrich K. Schnoes, Ronald F. Horst, 1 Richard
M. Shepard, and Neal A. Jorgensen abstract: A major vitamin D metabolite was isolated in …

Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in …

LA Romanyshyn, JK Wichmann… - Therapeutic drug …, 1994 - journals.lww.com
An isocratic liquid-chromatographic method employing one extraction step has been developed
for the quantitation of five drugs and three metabolites in human plasma. The method …

Role of kidney tissue in the production of 25-hydroxyvitamin D3-26, 23-lactone and 1 alpha, 25-dihydroxyvitamin D3-26, 23-lactone.

Y Tanaka, JK Wichmann, HE Paaren… - Proceedings of the …, 1980 - National Acad Sciences
Labeled 25-hydroxyvitamin D3-26,23-lactone was isolated from the serum of vitamin D-repleted
rats given [3 alpha-3H]-25-hydroxyvitamin D324 hr prior to sacrifice. The metabolite was …

Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia

CG Wasterlain, LM Adams, JK Wichmann, RD Sofia - Stroke, 1996 - Am Heart Assoc
Background and Purpose Felbamate, a novel anticonvulsant that binds to the glycine site of
the N-methyl-d-aspartate receptor, has been shown to have neuroprotective properties in …

High performance liquid chromatographic determination of azelastine and desmethylazelastine in guinea pig plasma and lung tissue

CN Langevin, J Pivonka, JK Wichmann… - Biomedical …, 1993 - Wiley Online Library
Analytical methods have been developed for the simultaneous quantitation of azelastine (AZ)
and desmethylazelastine (DAZ) in guinea pig plasma and lung tissue. The methods …

Pharmacokinetics of felbamate in pediatric and adult beagle dogs

VE Adusumalli, JR Gilchrist, JK Wichmann… - …, 1992 - Wiley Online Library
The relative bioavailability and pharmacokinetics of felbamate (FBM) after a single oral dose
and after 10 once‐daily oral doses of 60 mg/kg were investigated in adult and pediatric …

Isolation and identification of 23, 25-dihydroxyvitamin D3, an in vivo metabolite of vitamin D3

Y Tanaka, JK Wichmann, HK Schnoes, HF DeLuca - Biochemistry, 1981 - ACS Publications
Yoko Tanaka, Joseph K. Wichmann, Heinrich K. Schnoes, and Hector F. DeLuca* abstract:
Vitamin D supplemented rats produce a metabolite of 25-hydroxy [3a-3H] vitamin D3 that is …

Posthypoxic treatment with felbamate is neuroprotective in a rat model of hypoxia‐ischemia

…, PH Schwartz, H Hattori, RD Sofia, JK Wichmann - Neurology, 1993 - AAN Enterprises
Felbamate, a novel dicarbamate anticonvulsant that blocks the glycine site of the N-methyl-D-aspartate
receptor and protects the hippocampal slice from hypoxic damage, shows …

1, 25-Dihydroxyvitamin D3 stimulated increase of 7, 8-didehydrocholesterol levels in rat skin

RP Esvelt, HF DeLuca, JK Wichmann, S Yoshizawa… - Biochemistry, 1980 - ACS Publications
Robert P. Esvelt, Hector F. DeLuca,* Joseph K. Wichmann, Setsuko Yoshizawa, Jackie
Zurcher, Madabanada Sar,! and Walter E. Stumpf abstract: A convenient, accurate assay was …

Evidence for origin of insect sex pheromones: presence in food plants

LB Hendry, JK Wichmann, DM Hindenlang… - Science, 1975 - science.org
Compounds identified as sex attractant pheromones in a number of phytophagous insects
were found in a variety of host plants. These agents vary in chemical composition in different …