[BOOK][B] Linear algebraic groups

JE Humphreys - 2012 - books.google.com
James E. Humphreys is presently Professor of Mathematics at the University of Massachusetts
at Amherst. Before this, he held the posts of Assistant Professor of Mathematics at the …

[BOOK][B] Reflection groups and Coxeter groups

JE Humphreys - 1992 - books.google.com
… In this graduate textbook Professor Humphreys presents a concrete and up-todate introduction
to the theory of Coxeter groups. He assumes that the reader has a good knowledge of …

[BOOK][B] Introduction to Lie algebras and representation theory

JE Humphreys - 2012 - books.google.com
This book is designed to introduce the reader to the theory of semisimple Lie algebras over
an algebraically closed field of characteristic 0, with emphasis on representations. A good …

[BOOK][B] Representations of Semisimple Lie Algebras in the BGG Category

JE Humphreys - 2008 - books.google.com
Humphreys [125, $9 then defines an abstract root system in a finite dimensional euclidean
space E over R, with inner product denoted (A, u), to be a finite set q of vectors spanning E …

Rational use of in vitro P-glycoprotein assays in drug discovery

JW Polli, SA Wring, JE Humphreys, L Huang… - … of Pharmacology and …, 2001 - ASPET
P-glycoprotein (Pgp) affects the absorption, distribution, and clearance of a variety of
compounds. Thus, identification of compounds that are Pgp substrates can aid drug candidate …

Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs

KMM Doan, JE Humphreys, LO Webster… - … of Pharmacology and …, 2002 - ASPET
Membrane permeability and P-glycoprotein (Pgp) can be limiting factors for blood-brain barrier
penetration. The objectives of this study were to determine whether there are differences …

[BOOK][B] Conjugacy classes in semisimple algebraic groups

JE Humphreys - 1995 - books.google.com
Provides a useful exposition of results on the structure of semisimple algebraic groups over
an arbitrary algebraically closed field. After the fundamental work of Borel and Chevalley in …

[BOOK][B] Modular representations of finite groups of Lie type

JE Humphreys - 2006 - books.google.com
Finite groups of Lie type encompass most of the finite simple groups. Their representations
and characters have been studied intensively for half a century, though some key problems …

In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates

J Rautio, JE Humphreys, LO Webster… - Drug metabolism and …, 2006 - ASPET
Because modulation of P-glycoprotein (Pgp) through inhibition or induction can lead to drug-drug
interactions by altering intestinal, central nervous system, renal, or biliary efflux, it is …

In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor

…, GT Generaux, H Tracey, JE Humphreys… - Drug Metabolism and …, 2013 - ASPET
Dolutegravir (DTG; S/GSK1349572) is a potent HIV-1 integrase inhibitor with a distinct resistance
profile and a once-daily dose regimen that does not require pharmacokinetic boosting. …