Effect of amphetamine on the pressor response to tyramine: Formation of p‐hydroxynorephedrine from amphetamine in man

JH Cavanaugh, JD Griffith… - Clinical Pharmacology & …, 1970 - Wiley Online Library
The effect of amphetamine on the pressor sensitivity to the indirectly acting amine, tyramine,
and to norepinephrine was determined in 6 male patients. Acute intravenous administration …

Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers

…, CS Locke, CJ Eason, JH Cavanaugh… - British journal of …, 1998 - Wiley Online Library
Aims To assess the effects of the protease inhibitor ritonavir on the pharmacokinetics of ethinyl
oestradiol in healthy female volunteers. Methods This was an open‐label, single centre …

Metabolism and disposition of clarithromycin in man.

…, KG Tolman, SW Sanders, JH Cavanaugh - Drug metabolism and …, 1990 - ASPET
The metabolic fate and pharmacokinetics of clarithromycin following a single 250- or 1200-mg
oral dose of 14C-clarithromycin were studied in six healthy adult males. Peak plasma …

Guanethidine and related agents: III. Antagonism by drugs which inhibit the norepinephrine pump in man

JR Mitchell, JH Cavanaugh, L Arias… - The Journal of …, 1970 - Am Soc Clin Investig
Antagonism of the antihypertensive action of guanethidine by the tricyclic antidepressants,
desipramine and protriptyline, has been demonstrated in controlled studies. These …

Gastrointestinal motor effects of erythromycin in humans

…, CM Wood, RP Ryan, RC Arndorfer, JH Cavanaugh… - Gastroenterology, 1991 - Elsevier
The effects of an antibacterially effective IV dose of erythromycin on gastrointestinal motor
activity were investigated in eight normal healthy human volunteers in the fasted state and the …

Effect of valproate on the pharmacokinetics and pharmacodynamics of lorazepam

…, GF Witt, JH Cavanaugh - The Journal of …, 1997 - Wiley Online Library
The pharmacokinetic—pharmacodynamic interaction between valproate and lorazepam was
evaluated in this randomized, double‐blind, placebo‐controlled crossover study. Sixteen …

Single‐and multiple‐dose pharmacokinetics of clarithromycin, a new macrolide antimicrobial

…, CN Eason, JH Cavanaugh - The Journal of …, 1993 - Wiley Online Library
The pharmacokinetics of clarithromycin and its active 14(R)‐hydroxy metabolite were
evaluated after single and multiple oral doses of 250 and 500 mg of clarithromycin. Multiple‐dose …

The pharmacokinetics of zileuton in healthy young and elderly volunteers

…, CS Locke, JM Machinist, JH Cavanaugh… - Clinical …, 1995 - Springer
The effects of age and gender on the single and multiple dose pharmacokinetics of zileuton
have been examined in a phase I nonblinded study. A total of 27 healthy volunteers were …

Lansoprazole: administration of the contents of a capsule dosage formulation through a nasogastric tube

…, HH Shi, R Achari, S Dennis, JH Cavanaugh - Clinical …, 1996 - Elsevier
A single-dose, open-label, randomized, crossover bioavailability study was conducted in 24
healthy adult male volunteers to assess an alternative method of administration of …

Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium.

…, DW Schneck, JH Cavanaugh… - The Journal of clinical …, 1996 - europepmc.org
Background Valproic acid is added to the lithium regimens of many patients with bipolar
disorder, especially those with mania refractory to lithium treatment. Method We evaluated the …