Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs)

LS Birnbaum, DF Staskal, JJ Diliberto - Environment international, 2003 - Elsevier
This article reviews the state of the science regarding the health effects of polybrominated
dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). While thousands of articles have …

Adverse reproductive outcomes in the transgenic Ah receptor-deficient mouse

…, AR Buckalew, CR Wood, GA Held, JJ Diliberto - Toxicology and applied …, 1999 - Elsevier
The aryl hydrocarbon receptor (AHR) is a transcriptional regulatory protein that binds to
upstream DNA response elements of target genes. Activation of the AHR by binding of ligands …

Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups

…, VM Richardson, DG Ross, JJ Diliberto… - Toxicological …, 2009 - academic.oup.com
Previous studies demonstrated that perinatal exposure to polybrominated diphenyl ethers (PBDEs),
a major class of brominated flame retardants, may affect thyroid hormone (TH) …

Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener

…, DF Staskal, DG Ross, JJ Diliberto… - Toxicology and applied …, 2008 - Elsevier
Polybrominated diphenyl ethers (PBDEs) are a class of polyhalogenated aromatic compounds
commercially used as fire retardants in consumer products. These compounds have been …

Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time

DF Staskal, JJ Diliberto, MJ DeVito… - Toxicological …, 2005 - academic.oup.com
2,2′,4,4′-Tetrabromodiphenyl ether (BDE 47) is present in commercial mixtures of
polybrominated diphenyl ethers (PBDEs), which are used as flame retardants in a wide variety of …

Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice

DF Staskal, H Hakk, D Bauer, JJ Diliberto… - Toxicological …, 2006 - academic.oup.com
The congener profiles of polybrominated diphenyl ethers (PBDEs) in human and wildlife
samples are dominated by brominated diphenyl ether (BDE) congeners 47, 99, 100, 153, and …

Toxicokinetics of the flame retardant hexabromocyclododecane gamma: effect of dose, timing, route, repeated exposure, and metabolism

DT Szabo, JJ Diliberto, H Hakk, JK Huwe… - Toxicological …, 2010 - academic.oup.com
Hexabromocyclododecane-gamma (γ-HBCD) is the predominate diastereoisomer in the
commercial HBCD mixture used as a flame retardant in a wide variety of consumer products. …

Oxidative Stress in Female B6C3F1 Mice following Acute and Subchronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)

…, GE Hatch, MJ DeVito, JJ Diliberto… - Toxicological …, 2000 - academic.oup.com
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a highly persistent trace environmental
contaminant and is one of the most potent toxicants known to man. Hassoun et al. (1998, Toxicol. …

Role of CYP1A2 in hepatic sequestration of dioxin: studies using CYP1A2 knock-out mice

JJ Diliberto, D Burgin, LS Birnbaum - Biochemical and biophysical …, 1997 - Elsevier
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, dioxin), most potent of the polyhalogenated
aromatic hydrocarbons, has been studied in a variety of genetically normal species. Transgenic …

Toxicokinetics of the flame retardant hexabromocyclododecane alpha: effect of dose, timing, route, repeated exposure, and metabolism

DT Szabo, JJ Diliberto, H Hakk, JK Huwe… - Toxicological …, 2011 - academic.oup.com
Alpha-hexabromocyclododecane (α-HBCD) is an emerging persistent organic pollutant
present in the hexabromocyclododecane (HBCD) commercial mixture. HBCD is used as an …