Enzyme topology of intracellular membranes

JW DePierre, L Ernster - Annual Review of Biochemistry, 1977 - annualreviews.org
One of the most important results of studies on the membrane topology of the endoplasmic
reticulum is a model for how certain integral proteins bind to their membranes. Cytochrome b5…

[HTML][HTML] Plasma membranes of mammalian cells: a review of methods for their characterization and isolation

JW DePierre, ML Karnovsky - The Journal of cell biology, 1973 - ncbi.nlm.nih.gov
be considered in conjunction with data from similar studies on nonmammalian systems. The
reader is referred, for example, to work from Salton's laboratory on the cell membrane of …

Structural aspects of the membrane of the endoplasmic reticulum

JW Depierre, G Dallner - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1975 - Elsevier
The endoplasmic reticulum of the liver cell consists of a complex membrane network on
which are localized a large number of enzymes and enzyme systems. Among the functions …

Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver

MS Moron, JW Depierre, B Mannervik - Biochimica et biophysica acta (BBA …, 1979 - Elsevier
DEPIERRE and BENGT MANNERVIK … 18,279--290 35 DePierre, JW and Ernster, L. (1978)
Biochim. Biophys, … 38 Seidegard, J., DePierre, JW, Moron, MS, Johannesen, KAM and Ernster…

Tricyclic antidepressants inhibit IL-6, IL-1β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells

Z Xia, JW Depierre, L Nässberger - Immunopharmacology, 1996 - Elsevier
Tricyclic antidepressants (TCAs) are widely used in treating depressive disorders. It has been
demonstrated that, for instance, IL-1β and IL-6 inhibit the HPA axis, which plays a role in …

Microsomal Glutathione S‐Transferase: Purification, Initial Characterization and Demonstration that It Is not Identical to the Cytosolic Glutathione S‐Transferases A, B …

…, C Guthenberg, JW Depierre - European Journal of …, 1982 - Wiley Online Library
Rat liver microsomal glutathione S‐transferase was activated with N‐ethylmaleimide,
solubilized with Triton X‐100, and purified by chromatography on hydroxyapatite and CM‐…

Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid

…, XY Zhao, G Möller, BD Nelson, JW DePierre - International …, 2002 - Elsevier
In a previous investigation, we demonstrated that severe thymus and spleen atrophy occurs
in mice upon dietary exposure to several potent peroxisome proliferators (PPs). In the …

Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and …

…, D Grandér, MC Shoshan, JW DePierre - Toxicology and applied …, 2001 - Elsevier
We have previously shown that one of the most potent rodent hepatocarcinogens,
perfluorooctanoic acid (PFOA), induces apoptosis in human HepG2 cells in a dose- and time-…

Effects of peroxisome proliferators on the thymus and spleen of mice

Q Yang, Y Xie, JW Depierre - Clinical & Experimental …, 2000 - academic.oup.com
The effects of peroxisome proliferators on the immune system of male C57Bl/6 mice have
been investigated. Significant atrophy of the thymus and spleen was observed in animals …

Involvement of the peroxisome proliferator-activated receptor alpha in the immunomodulation caused by peroxisome proliferators in mice

…, Y Xie, SEH Alexson, BD Nelson, JW DePierre - Biochemical …, 2002 - Elsevier
Peroxisome proliferators (PPs) are a large class of structurally diverse chemicals, which
includes drugs designed to improve the metabolic abnormalities linking hypertriglyceridemia to …