Healing of duodenal ulcer with an antacid regimen

…, HD Frankl, CT Richardson, JI Isenberg… - … England Journal of …, 1977 - Mass Medical Soc
To determine whether a large-dose antacid regimen is effective in promoting healing of
duodenal ulcer, 74 patients with endoscopically proved duodenal ulcer completed a 28-day …

Gastroduodenal mucosal alkaline secretion and mucosal protection

G Flemstrom, JI Isenberg - Physiology, 2001 - journals.physiology.org
… , SE-751 23 Uppsala, Sweden, and JI Isenberg is in the Department of Medicine, University
… grant AM-33491 (to JI Isenberg) and the Ronald McDonald House Charities (to JI Isenberg). …

Impaired proximal duodenal mucosal bicarbonate secretion in patients with duodenal ulcer

JI Isenberg, JA Selling, DL Hogan… - New England Journal of …, 1987 - Mass Medical Soc
The defensive factors that prevent the human duodenal mucosa from acidic and peptic
damage have not been fully evaluated. To determine whether duodenal mucosal bicarbonate …

Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile

…, JI Schwartz, KC Lasseter, BJ Gertz, JI Isenberg… - Drug metabolism and …, 1997 - ASPET
Montelukast sodium [1-{[(1(R)-(3-(2-(7-chloro-2-quinolinyl)-(E)- ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio]methyl}cyclopropylacetic
acid sodium salt] (MK-476, …

Gastroduodenal bicarbonate secretion

…, MA Ainsworth, JI Isenberg - Alimentary pharmacology …, 1994 - Wiley Online Library
The gastroduodenal epithelium is covered by an adherent mucus layer into which bicarbonate
is secreted by surface epithelial cells. This mucus‐bicarbonate barrier is an important first …

CFTR mediates cAMP-and Ca2+-activated duodenal epithelial HCO3-secretion

DL Hogan, DL Crombie, JI Isenberg… - American Journal …, 1997 - journals.physiology.org
The role of the cystic fibrosis transmembrane conductance regulator (CFTR) in duodenal
alkaline secretion has not been directly examined. The aims of this series of experiments were …

Zollinger-Ellison syndrome

JI Isenberg, JH Walsh, MI Grossman - Gastroenterology, 1973 - Elsevier
It is now unequivocally established that ZES is caused by a tumor of the pancreas or duodenum
that secretes excessive amounts of gastrin. Therefore we encourage the use of the term …

Patient acceptance and effectiveness of a balanced lavage solution (Golytely) versus the standard preparation for colonoscopy

G Thomas, S Brozinsky, JI Isenberg - Gastroenterology, 1982 - Elsevier
An oral electrolyte solution containing 125 mM/L sodium, 10 mM/L potassium, 80 mM/L sulfate,
20 mM/L bicarbonate, and 80 mM of polyethylene glycol, and associated with little water …

Midazolam, a new more potent benzodiazepine, compared with diazepam: a randomized, double-blind study of preendoscopic sedatives

SG Cole, S Brozinsky, JI Isenberg - Gastrointestinal endoscopy, 1983 - Elsevier
Midazolam is a new imidazobenzodiazepine. It is more potent and has a snorter duration of
action than diazepam. Forty patients undergoing upper gastrointestinal endoscopy for the …

Randomized trials of endoscopic therapy and transjugular intrahepatic portosystemic shunt versus portacaval shunt for emergency and elective treatment of bleeding …

MJ Orloff, RJ Hye, HO Wheeler, JI Isenberg, KS Haynes… - Surgery, 2015 - Elsevier
Importance Bleeding esophageal varices has been studied extensively, but bleeding gastric
varices (BGV) has received much less investigation. However, BGV has been reported in ≤…