[HTML][HTML] Rivaroxaban with and without amiodarone in renal impairment

EJY Cheong, JJN Goh, Y Hong, P Kojodjojo… - Journal of the American …, 2018 - jacc.org
Rivaroxaban undergoes hepatic metabolism by cytochrome P450 (CYP) enzymes (CYP3A4
and CYP2J2) and renal excretion via P-glycoprotein (P-gp)–mediated secretion (1). …

Application of static modeling in the prediction of in vivo drug–drug interactions between rivaroxaban and antiarrhythmic agents based on in vitro inhibition studies

EJY Cheong, JJN Goh, Y Hong, G Venkatesan… - Drug Metabolism and …, 2017 - ASPET
Rivaroxaban, a direct Factor Xa inhibitor, is indicated for stroke prevention in nonvalvular
atrial fibrillation (AF). Studies have revealed that the clearance of rivaroxaban is largely …

Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR

HO Ng Tsai, JJN Goh, JWX Aw, Y Lin… - Journal of thrombosis …, 2018 - Springer
The objectives of this study are to compare steady-state trough (Cmin,ss) and peak (Cmax,ss)
concentrations of rivaroxaban between Asians and Caucasians and to evaluate the …

[HTML][HTML] Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants

JJN Goh, J Behn, CS Chong, G Zhong… - Archives of …, 2021 - Springer
Cytochrome P450 1A1 (CYP1A1) metabolizes estrogens, melatonin, and other key
endogenous signaling molecules critical for embryonic/fetal development. The enzyme has …

Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs

JP Ernest, JJN Goh, N Strydom, Q Wang… - European …, 2023 - Eur Respiratory Soc
Background: Phase 2a trials in tuberculosis typically use early bactericidal activity (EBA),
the decline in sputum CFU over 14 days, as the primary end-point for testing the efficacy of …

Pharmacology in the Context of Pathogenic and Non Pathogenic Bacteria

JJN Goh - 2023 - search.proquest.com
Janice Jia Ni GohJanice Jia Ni Goh Abstract … Ernest (JE), Janice Jia Ni Goh (JG), Natasha
Strydom(NS), Qianwen Wang(QW), Rob Christiaan van Wijk (RW), and Nan Zhang (NZ) and …

Pharmacology in the context of pathogenic and non pathogenic bacteria

J Goh Jia Ni - 2023 - escholarship.org
Janice Jia Ni GohJanice Jia Ni Goh Abstract … Ernest (JE), Janice Jia Ni Goh (JG), Natasha
Strydom(NS), Qianwen Wang(QW), Rob Christiaan van Wijk (RW), and Nan Zhang (NZ) and …

[HTML][HTML] LSTrAP-Crowd: prediction of novel components of bacterial ribosomes with crowd-sourced analysis of RNA sequencing data

B Hew, QW Tan, W Goh, JWX Ng, M Mutwil - BMC biology, 2020 - Springer
Background Bacterial resistance to antibiotics is a growing health problem that is projected
to cause more deaths than cancer by 2050. Consequently, novel antibiotics are urgently …

Features and Functionalities of Medical Mobile Applications for the Endemic Phase of COVID‐19: Review and Content Analysis

MJ Loy, KW Goh, N Osili, LC Ming… - … in Microbes and …, 2022 - repository.unair.ac.id
The study's objective was to assess the features and content of the COVID-19 mobile
applications accessible in the Apple AppStore. A content analysis, comparison, and functionality …

[PDF][PDF] FOREWORDS

I Ng - 2019 - singhealthdukenus.com.sg
It’s been six years since the SingHealth Duke-NUS Obstetrics and Gynaecology Academic
Clinical Programme (OBGYN ACP) was launched, and we look back with pride at the …