The use of the dual recombinase-mediated intersectional genetic approach involving Cre-loxP
and Dre-rox has significantly enhanced the precision of in vivo lineage tracing, as well as …

Background Fluid therapy for severe acute pancreatitis (SAP) should not only resolve deficiency
of blood volume, but also prevent fluid sequestration in acute response stage. Up to date…

… Department of Surgical Intensive Care Unit (Mao EQ, Fei J, Huang J, Tang YQ and Zhang
SD)… MAO En-qiang and FEI Jian contributed to this work equally. This research was supported …

The Cre–loxP recombination system is the most widely used technology for in vivo tracing of
stem or progenitor cell lineages. The precision of this genetic system largely depends on …

Sepsis is a significant public healthcare problem, affecting millions of people worldwide each
year, killing one in four, and increasing in incidence. Thus, advanced therapeutic strategies …

The identification of synergistic chemotherapeutic agents from a large pool of candidates is
highly challenging. Here, we present a Ranking-system of Anti-Cancer Synergy (RACS) that …

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined
factors. The low efficiency of reprogramming and genomic integration of oncogenes and viral …

γ-Aminobutyric acid (GABA) transporter subtype 1 (GAT1), which transports extracellular GABA
into presynaptic neurons, plays an important regulatory role in the function of GABAergic …

As a treatment option for cancer, thermal ablation has satisfactory effects on many types of
solid tumors (such as liver and renal cancers). However, its clinical applications for the …

Atherosclerosis, which is a primary cause of cardiovascular disease (CVD) deaths around
the world, is a chronic inflammatory disease that is characterised by the accumulation of lipid …