User profiles for Jochen Klein
jochen kleinMainz, Amarillo, Frankfurt Verified email at em.uni-frankfurt.de Cited by 6988 |
Robust independent validation of experiment and theory: Rivet version 3
…, C Gutschow, P Karczmarczyk, J Klein… - SciPost physics, 2020 - scipost.org
First released in 2010, the Rivet library forms an important repository for analysis code,
facilitating comparisons between measurements of the final state in particle collisions and …
facilitating comparisons between measurements of the final state in particle collisions and …
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes
…, V Chubanov, T Gudermann, J Klein… - Proceedings of the …, 2014 - National Acad Sciences
Chemosensory cells in the mucosal surface of the respiratory tract (“brush cells”) use the
canonical taste transduction cascade to detect potentially hazardous content and trigger local …
canonical taste transduction cascade to detect potentially hazardous content and trigger local …
Excessive hippocampal acetylcholine levels in acetylcholinesterase‐deficient mice are moderated by butyrylcholinesterase activity
Central cholinergic systems are involved in a plethora of brain functions and are severely
and selectively damaged in neurodegenerative diseases such as Alzheimer’s disease and …
and selectively damaged in neurodegenerative diseases such as Alzheimer’s disease and …
Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients
Experimental and clinical studies give evidence for breakdown of membrane phospholipids
during neurodegeneration. In the present study, we measured the levels of …
during neurodegeneration. In the present study, we measured the levels of …
Metabolism of boswellic acids in vitro and in vivo
Boswellia serrata resin dry extract is among the few herbal remedies designated with an
orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (…
orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (…
[PDF][PDF] Chemosensory cell-derived acetylcholine drives tracheal mucociliary clearance in response to virulence-associated formyl peptides
…, V Chubanov, T Gudermann, J Oberwinkler, J Klein… - Immunity, 2020 - cell.com
Mucociliary clearance through coordinated ciliary beating is a major innate defense removing
pathogens from the lower airways, but the pathogen sensing and downstream signaling …
pathogens from the lower airways, but the pathogen sensing and downstream signaling …
In vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery
…, WJ Geldenhuys, GA Gudelsky, J Klein… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Microdialysis is an important in vivo sampling technique, useful in assaying
extracellular tissue fluid. The technique has preclinical and clinical applications and is widely …
extracellular tissue fluid. The technique has preclinical and clinical applications and is widely …
Phosphocholine-modified macromolecules and canonical nicotinic agonists inhibit ATP-induced IL-1β release
…, V Mathes, T Timm, S Lerner, J Klein… - The Journal of …, 2015 - journals.aai.org
IL-1β is a potent proinflammatory cytokine of the innate immune system that is involved in host
defense against infection. However, increased production of IL-1β plays a pathogenic role …
defense against infection. However, increased production of IL-1β plays a pathogenic role …
Functions and pathophysiological roles of phospholipase D in the brain
J Klein - Journal of neurochemistry, 2005 - Wiley Online Library
Ten years after the isoforms of mammalian phospholipase D (PLD), PLD1 and 2, were
cloned, their roles in the brain remain speculative but several lines of evidence now implicate …
cloned, their roles in the brain remain speculative but several lines of evidence now implicate …
Free choline and choline metabolites in rat brain and body fluids: sensitive determination and implications for choline supply to the brain
J Klein, R Gonzalez, A Köppen, K Löffelholz - Neurochemistry international, 1993 - Elsevier
In the central nervous system, choline is an essential precursor of choline-containing
phospholipids in neurons and glial cells and of acetylcholine in cholinergic neurons. In order to …
phospholipids in neurons and glial cells and of acetylcholine in cholinergic neurons. In order to …