Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To identify
new susceptibility loci, we performed meta-analysis on genome-wide association study (…

The origin of most bacterial infections in the urinary tract is often presumed to be the gut.
Herein, we investigate the relationship between the gut microbiota and future development of …

Optic nerve degeneration caused by glaucoma is a leading cause of blindness worldwide.
Patients affected by the normal-pressure form of glaucoma are more likely to harbor risk …

Urinary tract infections are one of the most common infections in humans. Here we tested
the utility of urinary cell-free DNA (cfDNA) to comprehensively monitor host and pathogen …

Tacrolimus exhibits low and variable drug exposure after oral dosing, but the contributing
factors remain unclear. Based on our recent report showing a positive correlation between …

Purpose The CAV1/CAV2 (caveolin 1 and caveolin 2) genomic region previously was
associated with primary open-angle glaucoma (POAG), although replication among independent …

Posttransplant diarrhea is associated with kidney allograft failure and death, but its etiology
remains unknown in the majority of cases. Because altered gut microbial ecology is a …

High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens
in clinical samples. Conventional metagenomic sequencing, however, does not integrate …

Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a
challenging task because of much interpatient and intrapatient variability in drug absorption, …

Arguing that giving estrogen replacement therapy to women after menopause is medically
the wrong thing to do, Lee suggests that natural progesterone can prevent most of the …