The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3C-like protease inhibitor
PF-07321332 (nirmatrelvir), in combination with ritonavir (Paxlovid), was recently granted …

In this article, we prove that the complex convergence of the HCIZ free energy is equivalent
to the non-vanishing of the HCIZ integral in a neighbourhood of z= 0. Our approach is based …

Every compact topological group supports a unique translation invariant probability measure
on its Borel sets—the Haar measure. The Haar measure was first constructed for certain …

Sickle cell disease (SCD) is a genetic disorder caused by a single point mutation (β6 Glu →
Val) on the β-chain of adult hemoglobin (HbA) that results in sickled hemoglobin (HbS). In …

Enzymes of the UDP-glucuronosyltransferase (UGT) superfamily contribute to the
elimination of drugs from almost all therapeutic classes. Awareness of the importance of …

Quantitative characterization of UDP-glucuronosyltransferase (UGT) enzymes is valuable in
glucuronidation reaction phenotyping, predicting metabolic clearance and drug-drug …

In this paper, we study the relationship between polynomial integrals on the unitary group
and the conjugacy class expansion of symmetric functions in Jucys–Murphy elements. Our …

Hurwitz numbers count branched covers of the Riemann sphere with specified ramification
data, or equivalently, transitive permutation factorizations in the symmetric group with …

Human liver microsomes (HLM) and human hepatocytes (HHEP) are two common in vitro
systems used in metabolic stability and inhibition studies. The comparison between the assays …