O-linked N-acetylglucosamine (O-GlcNAc) is a reversible posttranslational modification of
Ser and Thr residues on cytosolic and nuclear proteins of higher eukaryotes catalyzed by O-…

Modification of small molecules and proteins by methyltransferases affects a wide range of
biological processes. Here, we report an enzyme-coupled continuous spectrophotometric …

Quorum sensing is a process by which bacteria sense cell density. This cell−cell communication
process is mediated by autoinducers. A cross-species messenger, autoinducer-2 (AI-2) …

Aldehyde oxidase (AO) is a complex molybdo-flavoprotein that belongs to the xanthine
oxidase family. AO is active as a homodimer, and each 150-kDa monomer binds two distinct […

DFT calculations support a concerted mechanism for xanthine oxidase and aldehyde
oxidase hydride displacement from the sp 2 carbon of 6-substituted 4-quinazolinones. The …

The ability of Leishmania to survive in their insect or mammalian host is dependent upon an
ability to sense and adapt to changes in the microenvironment. However, little is known …

S-Adenosylmethionine (AdoMet or SAM)-dependent methyltransferases belong to a large
and diverse family of group-transfer enzymes that perform vital biological functions on a host …

Bacterial quorum sensing is mediated by autoinducers, small signaling molecules
generated by bacteria. It has been proposed that the LuxS enzyme converts S-ribosyl-l-homocysteine …

Isoaspartate formation is a ubiquitous post-translation modification arising from spontaneous
asparagine deamidation or aspartate isomerization. The formation of isoaspartate inserts a …

Human aldehyde oxidase 1 (AOX1) has been subcloned into a vector suitable for expression
in Escherichia coli, and the protein has been expressed. The resulting protein is active, …