Behavioral approach to nondyskinetic dopamine antagonists: identification of seroquel
…, FM McLaren, CL Nelson, KM Kirkland - Journal of medicinal …, 2001 - ACS Publications
… , a major metabolite was observed in extracts of blood and urine by HPLC and the same
substance was also the major drug-related extractable component in rat brain tissue (Kirkland, …
substance was also the major drug-related extractable component in rat brain tissue (Kirkland, …
Comparison of a new ovomucoid and a second-generation α1-acid glycoprotein-based chiral column for the direct high-performance liquid chromatography resolution …
KM Kirkland, KL Neilson, DA McCombs - Journal of Chromatography A, 1991 - Elsevier
A new commercially-available glycoprotein chiral stationary phase (CSP) based on immobilized
ovomucoid protein has been evaluated. This column has been quantitatively compared …
ovomucoid protein has been evaluated. This column has been quantitatively compared …
Optimization of chiral selectivity on cellulose-based high-performance liquid chromatographic columns using aprotic mobile-phase modifiers
KM Kirkland - Journal of Chromatography A, 1995 - Elsevier
Tris-3,5-dimethyl phenyl carbamate-derivatized cellulose HPLC columns and other cellulose-based
columns are popular for the direct separation of many racemic drugs and …
columns are popular for the direct separation of many racemic drugs and …
Substituted 3-(phenylmethyl)-1H-indole-5-carboxamides and 1-(phenylmethyl) indole-6-carboxamides as potent, selective, orally active antagonists of the …
…, CK Buckner, EJ Kusner, KM Kirkland… - Journal of medicinal …, 1993 - ACS Publications
Substituted indole-5-carboxamidesand indole-6-carboxamides have been found to be potent
and selective antagonists of the peptidoleukotrienes. Initial derivatives of these series (4-[[5…
and selective antagonists of the peptidoleukotrienes. Initial derivatives of these series (4-[[5…
Changes in chiral selectivity with temperature for an ovomucoid protein-based column
KM Kirkland, DA McCombs - Journal of Chromatography A, 1994 - Elsevier
The effect of temperature on the direct HPLC separation of drug enantiomers was studied
for the commercially available ovomucoid protein chiral stationary phase. We confirm that …
for the commercially available ovomucoid protein chiral stationary phase. We confirm that …
Rapid, high-resolution high-performance liquid chromatographic analysis of antibiotics
KM Kirkland, DA McCombs, JJ Kirkland - Journal of Chromatography A, 1994 - Elsevier
A HPLC column devised for high separation speed combined with highly practical operating
features has been found useful for separating antibiotics. Important characteristics involve …
features has been found useful for separating antibiotics. Important characteristics involve …
New Third-Generation Protective Clothing from High-Performance Polyethylene Fiber: From Knives to Bullets
KM Kirkland, TY Tam, GC Weedon - 1991 - ACS Publications
Ultra high strength polyethylene fibers are finding increased use in a variety of protective
clothing applications. The unique combination of properties available with high performance …
clothing applications. The unique combination of properties available with high performance …
Research strategy for the HPLC/FT-IR analysis of drug metabolites
DE Pivonka, KM Kirkland - Applied spectroscopy, 1997 - opg.optica.org
A strategy for the infrared spectroscopic analysis of drug metabolites in high-pressure liquid
chromatography (HPLC) effluent is presented with a primary focus on delivery of metabolite …
chromatography (HPLC) effluent is presented with a primary focus on delivery of metabolite …
[HTML][HTML] Widespread reworking of Hadean-to-Eoarchean continents during Earth's thermal peak
… Stream sediment was systematically sampled at a density of one sample station per 20–50
km 2 over large parts of Greenland 13 . Streams with catchment areas <20 km 2 were chosen …
km 2 over large parts of Greenland 13 . Streams with catchment areas <20 km 2 were chosen …
Tracazolate metabolites in rat tissue.
FR Zuleski, KM Kirkland, MD Melgar… - Drug metabolism and …, 1985 - ASPET
Tracazolate (4-n-butylamino-1-ethyl-6-methyl-1H-pyrazolo[3,4-b] pyridine-5-carboxylic acid
ethyl ester) undergoes extensive biotransformation to lipophilic metabolites following oral …
ethyl ester) undergoes extensive biotransformation to lipophilic metabolites following oral …