This study demonstrates the feasibility of using nanoshells in vivo as a new contrast-enhancing
agent for photoacoustic tomography. Deep penetrating near-infrared light was employed …

Sixty‐five mothers and their 24‐month‐old toddlers were observed in a series of laboratory
procedures designed to assess relations between maternal interactive style and emotional, …

Understanding inter-subject variability in drug pharmacokinetics and pharmacodynamics is
important to ensure that all patients attain suitable drug exposure to achieve efficacy and …

Fifty‐six mothers and their 24‐month‐old toddlers were observed on two occasions in a
series of laboratory procedures designed to assess relations between emotional functioning (…

A study sample of 162 six‐month‐old children was selected from a larger sample of 346 infants
on the basis of parents' report of their infants' temperament and a laboratory assessment …

Ninety-nine 2-year-olds, out of a larger sample of 474 children, were classified as high (n =
49) or low (n = 50) in externalizing (aggressive/destructive) behaviors based on maternal …

Previous studies have shown the importance of the addition of albumin for characterization
of hepatic glucuronidation in vitro; however, no reports exist on the effects of albumin on …

New drugs may in some cases need to be tested in paediatric and pregnant patients.
However, it is difficult to recruit such patients and there are many ethical issues around their …

The ability to predict subcutaneous (SC) absorption rate and tissue distribution of
therapeutic proteins (TPs) using a bottom-up approach is highly desirable early in the drug …

This study aimed to derive quantitative abundance values for key hepatic transporters suitable
for in vitro–in vivo extrapolation within a physiologically based pharmacokinetic modeling …