A small hydrophilic peptide of eight amino acids (AspTyrLysAspAspAspAspLys) was engineered
onto the N-terminus of a variety of recombinant lymphokines for the purpose of aiding in …

Both IL-1 alpha and IL-1 beta are initially translated as approximately Mr 30,000 polypeptides
and processed to approximately Mr 17,500 prior to, or during, release from macrophages. …

Interleukin-1 beta (IL-1 beta) is derived from an inactive precursor by proteolytic cleavage.
To study IL-1 beta processing, we expressed the precursor in Escherichia coli, partially …

Exendin-4, a 39 amino acid peptide originally isolated from the oral secretions of the lizard
Heloderma suspectum, has been shown to share certain activities with glucagon-like-peptide-…

We report a straightforward methodology for purification of recombinant proteins by
incorporating a short hydrophilic peptide marker segment at their N-termini. A calcium-dependent …

The ability of interleukin-7 (IL-7) to stimulate murine thymocyte proliferation was investigated.
IL-7, either alone or in concert with lectin, induced proliferation of adult thymocytes as well …

There have been two recent reports suggesting that 3 10 helices can be distinguished from
α helices by circular dichroism. The differentiating feature is stated to be a [θ] 222 :[θ] 208 …

The detection and localization of interleukin (IL) 1 in human monocytes was carried out by
flow cytometry using monoclonal antibodies to IL-1 alpha and IL-1 beta proteins. IL-1 alpha …

Exendin-4 is a natural, 39-residue peptide first isolated from the salivary secretions of a Gila
Monster (Heloderma suspectum) that has some pharmacological properties similar to …

Interleukin 4 (IL-4) is secreted by activated T cells and pleiotropically modulates both B- and
T-lymphocyte function. In murine helper (CD4+) T-cell clones IL-4 production appears to be …