Oxidative stress: the lead or supporting actor in the pathogenesis of diabetic complications
T Kuroki, K Isshiki, GL King - Journal of the American Society of …, 2003 - journals.lww.com
… Keiji Isshiki received a mentor fellowship from the American Diabetes Association. … , Sawada
F, Toda G, Yamachika S, Seto S, Urata Y, Ihara Y, Sakata N, Taniguchi N, Kondo T, Yano K: …
F, Toda G, Yamachika S, Seto S, Urata Y, Ihara Y, Sakata N, Taniguchi N, Kondo T, Yano K: …
[HTML][HTML] Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
…, K Horiike, M Chin-Kanasaki, K Isshiki… - The Journal of …, 2010 - Am Soc Clin Investig
Mitochondrial oxidative damage is a basic mechanism of aging, and multiple studies
demonstrate that this process is attenuated by calorie restriction (CR). However, the molecular …
demonstrate that this process is attenuated by calorie restriction (CR). However, the molecular …
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
…, M HANEDA, H NAKAGAWA, K ISSHIKI… - The FASEB …, 2000 - Wiley Online Library
Activation of protein kinase C (PKC) is implicated as an important mechanism by which
diabetes causes vascular complications. We have recently shown that a PKC β inhibitor …
diabetes causes vascular complications. We have recently shown that a PKC β inhibitor …
[HTML][HTML] Behavior of Yersinia enterocolitica in Foods
ML Bari, MA Hossain, K Isshiki, D Ukuku - Journal of pathogens, 2011 - hindawi.com
Yersinia enterocolitica are ubiquitous, being isolated frequently from soil, water, animals,
and a variety of foods. They comprise a biochemically heterogeneous group that can survive …
and a variety of foods. They comprise a biochemically heterogeneous group that can survive …
[HTML][HTML] The GEOTRACES intermediate data product 2017
The GEOTRACES Intermediate Data Product 2017 (IDP2017) is the second publicly available
data product of the international GEOTRACES programme, and contains data measured …
data product of the international GEOTRACES programme, and contains data measured …
[PDF][PDF] Preliminary examination of allyl isothiocyanate vapor for food preservation
K Isshiki, K Tokuoka, R Mori, S Chiba - Bioscience, biotechnology …, 1992 - Taylor & Francis
The major pungent component of black mustard (Brassica nigra) and brown mustard (B.
juncea), which is the same as that of wasabi (Eutrema wasabi Maxim.), is allyl isothiocyanate (…
juncea), which is the same as that of wasabi (Eutrema wasabi Maxim.), is allyl isothiocyanate (…
[HTML][HTML] SIRT1 inhibits transforming growth factor β-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation
…, K Kanasaki, T Sugimoto, S Araki, K Isshiki… - Journal of Biological …, 2007 - ASBMB
SIRT1, a class III histone deacetylase, is considered a key regulator of cell survival and
apoptosis through its interaction with nuclear proteins. In this study, we have examined the …
apoptosis through its interaction with nuclear proteins. In this study, we have examined the …
Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C β2 activation and diabetes
KJ Way, K Isshiki, K Suzuma, T Yokota, D Zvagelsky… - Diabetes, 2002 - Am Diabetes Assoc
Protein kinase C (PKC) β isoform activity is increased in myocardium of diabetic rodents
and heart failure patients. Transgenic mice overexpressing PKCβ2 (PKCβ2Tg) in the …
and heart failure patients. Transgenic mice overexpressing PKCβ2 (PKCβ2Tg) in the …
Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet
…, T Uzu, S Araki, T Sugimoto, K Isshiki… - Journal of the …, 2007 - journals.lww.com
Metabolic syndrome is associated with increased risk of chronic kidney disease, and the renal
injury in patients with metabolic syndrome may be a result of altered renal lipid metabolism…
injury in patients with metabolic syndrome may be a result of altered renal lipid metabolism…
Structural and functional changes in the kidneys of high-fat diet-induced obese mice
…, M Soumura, T Sugimoto, K Isshiki… - American Journal …, 2009 - journals.physiology.org
Metabolic syndrome has been reported to be associated with chronic kidney disease, but the
mechanisms remain unclear. Although feeding of a high-fat diet (HFD) to C57BL/6 mice is …
mechanisms remain unclear. Although feeding of a high-fat diet (HFD) to C57BL/6 mice is …