User profiles for K. Taguchi

Keiko Taguchi

- Verified email at med.tohoku.ac.jp - Cited by 11370

Katsuyuki Taguchi

- Verified email at jhmi.edu - Cited by 6572

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

K Taguchi, H Motohashi, M Yamamoto - Genes to cells, 2011 - Wiley Online Library
… response and cancer evolution - Taguchi - 2011 - Genes to Cells - Wiley Online Library … to
DEM and tBHQ but not to 15d-PGJ 2 (K. Takaya and M. Yamamoto, unpublished observation). …

Vision 20/20: single photon counting x‐ray detectors in medical imaging

K Taguchi, JS Iwanczyk - Medical physics, 2013 - Wiley Online Library
… Characteristic K x-rays ranges are calculated for the averaged energies of K-alpha 1 and
K-alpha 2 because they are most prevalent. However, K x-rays ranges for K-betas are slightly …

[HTML][HTML] The KEAP1–NRF2 system in cancer

K Taguchi, M Yamamoto - Frontiers in oncology, 2017 - frontiersin.org
Cancer cells first adapt to the microenvironment and then propagate. Mutations in tumor
suppressor genes or oncogenes are frequently found in cancer cells. Comprehensive genomic …

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

M Komatsu, H Kurokawa, S Waguri, K Taguchi… - Nature cell …, 2010 - nature.com
Impaired selective turnover of p62 by autophagy causes severe liver injury accompanied by
the formation of p62-positive inclusions and upregulation of detoxifying enzymes. These …

Hard X-ray detector (HXD) on board Suzaku

…, M Sugiho, M Suzuki, K Taguchi… - Publications of the …, 2007 - academic.oup.com
The Hard X-ray Detector (HXD) on board Suzaku covers a wide energy range from 10 keV
to 600 keV by the combination of silicon PIN diodes and GSO scintillators. The HXD is …

[PDF][PDF] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming

Y Mitsuishi, K Taguchi, Y Kawatani, T Shibata… - Cancer cell, 2012 - cell.com
… P/K-Alb liver compared with the rest of the mice, suggesting the increased production of Nrf2
in the P/K… in the P/K-Alb mice. Importantly, Keap1 protein was barely detectable in either the …

Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum‐based chemotherapy

…, T Kita, M Suzuki, I Sato, K Taguchi - … Journal of the …, 2000 - Wiley Online Library
BACKGROUND A retrospective review of treatment results comparing women with clear cell
carcinoma of the ovary (CCC) with a group with serous adenocarcinoma of the ovary (SAC) …

[HTML][HTML] Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript

Y Shigeyoshi, K Taguchi, S Yamamoto, S Takekida… - Cell, 1997 - cell.com
To understand how light might entrain a mammalian circadian clock, we examined the effects
of light on mPer1, a sequence homolog of Drosophila per, that exhibits robust rhythmic …

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled …

…, S Ohtani, K Higaki, K Watanabe, K Taguchi… - The lancet …, 2017 - thelancet.com
Background ExteNET showed that 1 year of neratinib, an irreversible pan-HER tyrosine
kinase inhibitor, significantly improves 2-year invasive disease-free survival after trastuzumab-…

Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain–Barré syndrome

…, M Odaka, K Hirata, K Taguchi… - Proceedings of the …, 2004 - National Acad Sciences
Molecular mimicry between microbial and self-components is postulated as the mechanism
that accounts for the antigen and tissue specificity of immune responses in postinfectious …