The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
J Liu, M Gao, J He, K Wu, S Lin, L Jin, Y Chen, H Liu… - Nature, 2021 - nature.com
The RNA modification N 6 -methyladenosine (m 6 A) has critical roles in many biological
processes 1 , 2 . However, the function of m 6 A in the early phase of mammalian development …
processes 1 , 2 . However, the function of m 6 A in the early phase of mammalian development …
[HTML][HTML] Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
The majority of mammalian genomes are devoted to transposable elements (TEs). Whilst
TEs are increasingly recognized for their important biological functions, they are a potential …
TEs are increasingly recognized for their important biological functions, they are a potential …
[PDF][PDF] Resolving cell fate decisions during somatic cell reprogramming by single-cell RNA-Seq
L Guo, L Lin, X Wang, M Gao, S Cao, Y Mai, F Wu… - Molecular cell, 2019 - cell.com
Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs), which is a
highly heterogeneous process. Here we report the cell fate continuum during somatic cell …
highly heterogeneous process. Here we report the cell fate continuum during somatic cell …
[PDF][PDF] YTHDF2/3 are required for somatic reprogramming through different RNA deadenylation pathways
J Liu, M Gao, S Xu, Y Chen, K Wu, H Liu, J Wang… - Cell Reports, 2020 - cell.com
N 6 -methyladenosine (m 6 A), the most abundant reversible modification on eukaryote
messenger RNA, is recognized by a series of readers, including the YT521-B homology domain …
messenger RNA, is recognized by a series of readers, including the YT521-B homology domain …
[PDF][PDF] SETDB1-mediated cell fate transition between 2C-like and pluripotent states
Known as a histone H3K9 methyltransferase, SETDB1 is essential for embryonic development
and pluripotent inner cell mass (ICM) establishment. However, its function in pluripotency …
and pluripotent inner cell mass (ICM) establishment. However, its function in pluripotency …
Moment magnitudes of two large Turkish earthquakes on February 6, 2023 from long-period coda
Two large earthquakes (an earthquake doublet) occurred in south-central Turkey on February
6, 2023, causing massive damages and casualties. The magnitudes and the relative sizes …
6, 2023, causing massive damages and casualties. The magnitudes and the relative sizes …
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling
S Yu, C Zhou, S Cao, J He, B Cai, K Wu, Y Qin… - Nature cell …, 2020 - nature.com
BMP4 regulates a plethora of developmental processes, including the dorsal–ventral axis
and neural patterning. Here, we report that BMP4 reconfigures the nuclear architecture during …
and neural patterning. Here, we report that BMP4 reconfigures the nuclear architecture during …
Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation
FL Liu, K Wu, J Sun, Z Duan, X Quan… - National Science …, 2021 - academic.oup.com
About every 26 months, the distance between Earth and Mars reaches a minimum, and that
is the best time window for Mars exploration from Earth. In July 2020, three spacecraft started …
is the best time window for Mars exploration from Earth. In July 2020, three spacecraft started …
Proteomic changes in chicken primary hepatocytes exposed to T‐2 toxin are associated with oxidative stress and mitochondrial enhancement
P Mu, M Xu, L Zhang, K Wu, J Wu, J Jiang, Q Chen… - …, 2013 - Wiley Online Library
T ‐2 toxin is a mycotoxin that is toxic to plants, animals, and humans. However, its molecular
mechanism remains unclear, especially in chickens. In this study, using 2 D electrophoresis …
mechanism remains unclear, especially in chickens. In this study, using 2 D electrophoresis …
Dissipation behavior, residue distribution and risk assessment of three fungicides in pears
Q Fang, R Wu, G Hu, A Lai, K Wu… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND Fungicides are often applied to pears before they are kept in storage facilities.
The scientific application of pesticides can reduce unnecessary exposure, which in turn …
The scientific application of pesticides can reduce unnecessary exposure, which in turn …