Thrombocytopenia and anemia caused by a persistent high linezolid concentration in patients with renal dysfunction

…, A Mizoguchi, S Sadoh, Y Hiraki, K Matsumoto… - Journal of Infection and …, 2011 - Elsevier
It has been proposed that it is not necessary to adjust the dose of linezolid (LZD) in patients
with reduced renal function. However, significantly lower platelet counts and hemoglobin …

[HTML][HTML] K-point longitudinal acoustic phonons are responsible for ultrafast intervalley scattering in monolayer MoSe2

S Bae, K Matsumoto, H Raebiger, K Shudo… - Nature …, 2022 - nature.com
In transition metal dichalcogenides, valley depolarization through intervalley carrier scattering
by zone-edge phonons is often unavoidable. Although valley depolarization processes …

[HTML][HTML] Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins

…, D Hu, K Matsumoto, K Takeda, N Matsumoto… - Journal of Biological …, 2012 - ASBMB
Malectin is an endoplasmic reticulum-resident lectin, which recognizes di-glucosylated Glc
2 Man 9 GlcNAc 2 (G2M9) N-glycans on newly synthesized glycoproteins. We previously …

Correlation between serum linezolid concentration and the development of thrombocytopenia

…, M Hiraike, N Misumi, K Matsumoto… - … journal of infectious …, 2012 - Taylor & Francis
We evaluated the possible association between trough linezolid (LZD) concentrations and
platelet counts using a dose–response curve with a logit model equation. We demonstrated …

[HTML][HTML] Discovery of a new sialic acid binding region that regulates Siglec-7

…, T Takahashi, S Hanashima, K Matsumoto… - Scientific reports, 2020 - nature.com
Siglec-7 is a human CD33-like siglec, and is localised predominantly on human natural killer
(NK) cells and monocytes. Siglec-7 is considered to function as an immunoreceptor in a …

Characterization of antibody products obtained through enzymatic and nonenzymatic glycosylation Reactions with a glycan oxazoline and preparation of a …

S Manabe, Y Yamaguchi, K Matsumoto… - Bioconjugate …, 2019 - ACS Publications
Glycan engineering of antibodies has received considerable attention. Although various
endo-β-N-acetylglucosaminidase mutants have been developed for glycan remodeling, a side …

[HTML][HTML] Transferrin biosynthesized in the brain is a novel biomarker for Alzheimer's disease

…, Y Ugawa, T Saito, TC Saido, K Matsumoto… - Metabolites, 2021 - mdpi.com
Glycosylation is a cell type-specific post-translational modification that can be used for
biomarker identification in various diseases. Aim of this study is to explore glycan-biomarkers on …

Biological role of site-specific O-glycosylation in cell adhesion activity and phosphorylation of osteopontin

M Oyama, Y Kariya, Y Kariya, K Matsumoto… - Biochemical …, 2018 - portlandpress.com
Osteopontin (OPN) is an extracellular glycosylated phosphoprotein that promotes cell
adhesion by interacting with several integrin receptors. We previously reported that an OPN …

Population pharmacokinetic analysis of linezolid in low body weight patients with renal dysfunction

…, E Yukawa, Y Hiraki, K Matsumoto… - The Journal of …, 2013 - Wiley Online Library
Linezolid has antibacterial activity against aerobic Gram‐positive cocci, including methicillin‐resistant
Staphylococcus aureus (MRSA). Adjustment of the dose of linezolid has been …

DNA methyltransferase-and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development

S Go, H Kurita, M Hatano, K Matsumoto, H Nogawa… - Archives of …, 2021 - Springer
Methylmercury (MeHg) is a chemical substance that causes adverse effects on fetal
development. However, the molecular mechanisms by which environmental MeHg affects fetal …