Identification and quantification of daidzein-7-glucuronide-4′-sulfate, genistein-7-glucuronide-4′-sulfate and genistein-4′, 7-diglucuronide as major metabolites in …
K Hosoda, T Furuta, A Yokokawa, K Ishii - Analytical and bioanalytical …, 2010 - Springer
Much attention has been paid to the metabolism and disposition of isoflavones daidzein (Dein)
and genistein (Gein) with regard to the prevention of several hormone-dependent …
and genistein (Gein) with regard to the prevention of several hormone-dependent …
Metabolism and disposition of isoflavone conjugated metabolites in humans after ingestion of kinako
K Hosoda, T Furuta, K Ishii - Drug Metabolism and Disposition, 2011 - ASPET
Isoflavone aglycones daidzein (Dein) and genistein (Gein) are present primarily as
glucuronides and sulfates in human plasma; however, very little is known about the plasma …
glucuronides and sulfates in human plasma; however, very little is known about the plasma …
Plasma profiling of intact isoflavone metabolites by high-performance liquid chromatography and mass spectrometric identification of flavone glycosides daidzin and …
K Hosoda, T Furuta, A Yokokawa, K Ogura… - Drug Metabolism and …, 2008 - ASPET
The roles of isoflavones in the prevention of several hormone-dependent cancers and
osteoporosis are of great interest. Despite many pharmacokinetics studies of the isoflavones, the …
osteoporosis are of great interest. Despite many pharmacokinetics studies of the isoflavones, the …
Simultaneous determination of glucuronic acid and sulfuric acid conjugated metabolites of daidzein and genistein in human plasma by high-performance liquid …
K Hosoda, T Furuta, K Ishii - Journal of Chromatography B, 2010 - Elsevier
Isoflavone aglycones daidzein (Dein) and genistein (Gein) are mainly present as glucuronides
and sulfates in human plasma, and small amounts of the intact aglycones are also …
and sulfates in human plasma, and small amounts of the intact aglycones are also …
Intraindividual and interindividual variabilities in endogenous cortisol 6β-hydroxylation clearance as an index for in vivo CYP3A phenotyping in humans
H Shibasaki, K Hosoda, M Goto, A Suzuki… - Drug Metabolism and …, 2013 - ASPET
This study was designed to evaluate the in vivo activity of cytochrome P450 3A (CYP3A) in
49 healthy Japanese subjects aged 22–58 years using endogenous cortisol 6β-hydroxylation …
49 healthy Japanese subjects aged 22–58 years using endogenous cortisol 6β-hydroxylation …
Identification of equol‐7‐glucuronide‐4′‐sulfate, monoglucuronides and monosulfates in human plasma of 2 equol producers after administration of kinako by LC …
A Obara, M Kinoshita, K Hosoda… - Pharmacology …, 2019 - Wiley Online Library
Equol is a product formed during the biotransformation of the naturally occurring isoflavone
daidzein by intestinal bacteria. The role of equol in the prevention of several hormone‐…
daidzein by intestinal bacteria. The role of equol in the prevention of several hormone‐…
Isoflavones: high-performance liquid chromatographic analysis of glucuronic acid-and sulfuric acid-conjugated metabolites of daidzein and genistein in human …
K Ishii, K Hosoda, T Furuta - 2012 - books.rsc.org
Several methods for the determination of glucuronic acid-and/or sulfuric acid-conjugated
metabolites of daidzein and genistein in human plasma have been reported. The methods can …
metabolites of daidzein and genistein in human plasma have been reported. The methods can …
TAKASHIFURUTAb
K ISHII, K HOSODA - Isoflavones: Chemistry, Analysis, Function …, 2012 - books.google.com
The effect on human health of the isoflavones daidzein and genistein has been widely
studied. These isoflavones are thought to play a role in the prevention of various hormone-…
studied. These isoflavones are thought to play a role in the prevention of various hormone-…
Intra-and Inter-individual Variabilities in Endogenous Cortisol 6β-hydroxylation Clearance as an Index for in Vivo CYP3A Phenotyping in Humans
H Shibasaki, K Hosoda, M Goto, A Suzuki… - Drug Metabolism and …, 2012 - ASPET
The present study was designed to evaluate the in vivo activity of cytochrome P450 3A (CYP3A)
in 49 healthy Japanese subjects aged 22-58 years using endogenous cortisol 6β-…
in 49 healthy Japanese subjects aged 22-58 years using endogenous cortisol 6β-…
[CITATION][C] Plasma profiling of intact isoflavone metabolites by HPLC and mass spectrometric identification of flavone glycosides, daidzin and genistin in human …
K Hosoda, T Furuta, A Yokokawa, K Ogura… - Drug Metabolism and …, 2008 - ASPET
The roles of isoflavones in the prevention of several hormone-dependent cancers and
osteoporosis are of great interest. Despite many pharmacokinetics studies of the isoflavones, …
osteoporosis are of great interest. Despite many pharmacokinetics studies of the isoflavones, …