Type I collagen-PEO fibers and non-woven fiber networks were produced by the electrospinning
of a weak acid solution of purified collagen at ambient temperature and pressure. As …

The effectiveness of photomediated cross-linking of type I collagen gels in the presence of
rat aortic smooth muscle cells (RASMC) as a method to enhance gel mechanical properties …

With three FDA-approved products, lipid nanoparticles (LNPs) are under intensive development
for delivering wide-ranging nucleic acid therapeutics. A significant challenge for LNP …

Pharmaceutical scientists are currently facing an increasing number of drug molecules with
less than ideal properties such as poor solubility and lack of acceptable physical and …

Recombinant DNA synthesis was employed to produce elastin–mimetic protein triblock
copolymers containing chemically distinct midblocks. These materials displayed a broad range …

Solid-state cross-linking of elastin−mimetic fibers was investigated. Through available
lysine residues, an elastin−mimetic protein polymer, poly((Val-Pro-Gly-Val-Gly) 4 (Val-Pro-Gly-Lys-…

Micro- and nano-carrier formulations have been developed as drug delivery systems for
active pharmaceutical ingredients (APIs) that suffer from poor physico-chemical, …

The application of twin screw extrusion (TSE) as a scalable and green process for the
manufacture of cocrystals was investigated. Four model cocrystal forming systems, Caffeine-Oxalic …

Purpose To study crystal growth rates of amorphous griseofulvin (GSF) below its glass
transition temperature (T g ) and the effect of surface crystallization on the overall crystallization …

The well accepted “free drug hypothesis” for small-molecule drugs assumes that only the
free (unbound) drug concentration at the therapeutic target can elicit a pharmacologic effect. …