Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary
culture of human hepatocytes and measuring CYP3A4 mRNA, protein and microsomal activity…

The aim of this study was to test suitable culture conditions for maintaining normal cellular
cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by …

The aim of this study was to determine the in vitro and in vivo effects of several prototypical
inducers, namely β-naphthoflavone, 3-methylcholanthrene, phenobarbital, isoniazid, rifampin…

In the present study, we evaluated the inducibility of cytochrome P-450 (CYP) CYP1A, CYP2B,
CYP3A, and CYP4A by β-naphthoflavone, phenobarbital, dexamethasone, and clofibric …

The effect of medium formulation, composition of extracellular matrix overlay, and culture
dish material on liver microsomal cytochrome P-450 (CYP) 2B induction by phenobarbital (PB) …

This IBM® Redbooks® publication describes the new Rational® Unified Process®(RUP®)
for System z™ method, which has been especially created for use by organizations that are …

Twenty well-trained runners (VO2max 4.6+/-0.5 L x min [-1]) were age and ability matched
and assigned to either a cross training (CT) or run only group (RT). All subjects maintained …

Objective: To examine the effects of an increased training load and period of detraining on
testicular function in male distance runners. Design: Multiple-group time-series design using …

We investigated the effect of ≥8 months of 40% caloric restriction (CR) on photoreceptor
cell loss in 12, 18, and 24 month-old Fischer 344 rats (N = 154). Rats were reared at the NIA …

Iron deficiency may lead to anemia and may result in compromised endurance exercise
performance, Iron deficiency has also been reported to adversely affect the immune system and …