Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults
…, A Al-Attar, BJ Shelton, KJ Holt… - The Journal of …, 2011 - journals.aai.org
NK cells are essential for health, yet little is known about human NK turnover in vivo. In both
young and elderly women, all NK subsets proliferated and died more rapidly than T cells. …
young and elderly women, all NK subsets proliferated and died more rapidly than T cells. …
Prediction of tissue-plasma partition coefficients using microsomal partitioning: Incorporation into physiologically based pharmacokinetic models and steady-state …
K Holt, M Ye, S Nagar, K Korzekwa - Drug metabolism and disposition, 2019 - ASPET
Drug distribution is a necessary component of models to predict human pharmacokinetics.
A new membrane-based tissue-plasma partition coefficient (K p ) method (K p,mem ) to …
A new membrane-based tissue-plasma partition coefficient (K p ) method (K p,mem ) to …
Towards a wearable cough detector based on neural networks
…, H Ren, J Smith, K McGuinnes, K Holt… - … , Speech and Signal …, 2018 - ieeexplore.ieee.org
Persistent cough is a symptom common to a number of respiratory disorders; however, reliable
monitoring of cough frequency and cough severity over an extended period of time can …
monitoring of cough frequency and cough severity over an extended period of time can …
Investigating the safety of capsaicin cough challenge in severe asthma.
…, SJ Fowler, R Niven, D Ryan, K Holt… - Clinical & …, 2019 - search.ebscohost.com
The article presents a study which examined the safety and feasibility of conducting capsaicin
cough challenges in severe asthma patients. Other topics include some possible adverse …
cough challenges in severe asthma patients. Other topics include some possible adverse …
Numerical modeling and test data comparison of propulsion test article helium pressurization system
K Holt, A Majumdar, T Steadman… - 36th AIAA/ASME/SAE …, 2000 - arc.aiaa.org
A transient model of the propulsion test article.(PTA) helium pressurization system was
developed using the generalized fluid system simulation program (GFSSP). The model included …
developed using the generalized fluid system simulation program (GFSSP). The model included …
Methods to predict volume of distribution
K Holt, S Nagar, K Korzekwa - Current pharmacology reports, 2019 - Springer
Purpose of Review Prior to human studies, knowledge of drug disposition in the body is useful
to inform decisions on drug safety and efficacy, first in human dosing, and dosing regimen …
to inform decisions on drug safety and efficacy, first in human dosing, and dosing regimen …
[BOOK][B] When Zachary Beaver came to town
KW Holt - 2011 - books.google.com
National Book Award Winner The red words painted on the trailer caused quite a buzz
around town and before an hour was up, half of Antler was standing in line with two dollars …
around town and before an hour was up, half of Antler was standing in line with two dollars …
Modeling and test data analysis of a tank rapid chill and fill system for the advanced shuttle upper stage (ASUS) concept
RH Flachbart, A Hedayat, KA Holt - AIP Conference Proceedings, 2002 - pubs.aip.org
The Advanced Shuttle Upper Stage (ASUS) concept addresses safety concerns associated
with cryogenic stages by launching empty, and filling on ascent. The ASUS employs a rapid …
with cryogenic stages by launching empty, and filling on ascent. The ASUS employs a rapid …
ZnS nanocrystal cytotoxicity is influenced by capping agent chemical structure and duration of time in suspension
…, VJ Chehata, MP Schmidt, KL Holt… - Journal of Applied …, 2013 - Wiley Online Library
As a result of their characteristic physical and optical properties, including their size, intense
fluorescence, broad excitation, narrow emission and resistance to photobleaching, …
fluorescence, broad excitation, narrow emission and resistance to photobleaching, …
[BOOK][B] My Louisiana Sky
KW Holt - 2011 - books.google.com
Tiger Ann Parker wants nothing more than to get out of the rural town of Saitter, Louisiana--far
away from her mentally disabled mother, her" slow" father who can't read an electric bill, …
away from her mentally disabled mother, her" slow" father who can't read an electric bill, …