Did you mean: Kimon. Kanellakis
[HTML][HTML] Different regions of the immunophilin FKBP52 determine its association with the glucocorticoid receptor, hsp90, and cytoplasmic dynein
…, MD Galigniana, KC Kanelakis, C Radanyi… - Journal of Biological …, 1999 - ASBMB
FKBP52 is a high molecular mass immunophilin possessing peptidylprolyl isomerase (PPIase)
activity that is inhibited by the immunosuppressant drug FK506. FKBP52 is a component …
activity that is inhibited by the immunosuppressant drug FK506. FKBP52 is a component …
[HTML][HTML] Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo
…, AM Silverstein, DR Demady, KC Kanelakis… - Journal of Biological …, 1999 - ASBMB
It is established that the multiprotein heat shock protein 90 (hsp90)-based chaperone
system acts on the ligand binding domain of the glucocorticoid receptor (GR) to form a GR·hsp90 …
system acts on the ligand binding domain of the glucocorticoid receptor (GR) to form a GR·hsp90 …
[HTML][HTML] The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client …
Y Morishima, KC Kanelakis, PJM Murphy… - Journal of Biological …, 2003 - ASBMB
A variety of signaling proteins form heterocomplexes with and are regulated by the heat
shock protein chaperone hsp90. These complexes are formed by a multiprotein machinery, …
shock protein chaperone hsp90. These complexes are formed by a multiprotein machinery, …
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective …
…, HL Palomino, TI Brondstetter, KC Kanelakis… - Molecular …, 2011 - ASPET
The hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) enzymes represent novel targets
for the treatment of anemia, ulcerative colitis, and ischemic and metabolic disease inter alia…
for the treatment of anemia, ulcerative colitis, and ischemic and metabolic disease inter alia…
[HTML][HTML] The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system
Y Morishima, KC Kanelakis, AM Silverstein… - Journal of Biological …, 2000 - ASBMB
A system consisting of five purified proteins: Hsp90, Hsp70, Hop, Hsp40, and p23, acts as a
machinery for assembly of glucocorticoid receptor (GR)·Hsp90 heterocomplexes. Hop binds …
machinery for assembly of glucocorticoid receptor (GR)·Hsp90 heterocomplexes. Hop binds …
Characterization of a plant homolog of hop, a cochaperone of hsp90
Z Zhang, MK Quick, KC Kanelakis, M Gijzen… - Plant …, 2003 - academic.oup.com
The 90-kD molecular chaperone hsp90 is the key component of a multiprotein chaperone
complex that facilitates folding, stabilization, and functional modulation of a number of …
complex that facilitates folding, stabilization, and functional modulation of a number of …
[HTML][HTML] Stoichiometry, abundance, and functional significance of the hsp90/hsp70-based multiprotein chaperone machinery in reticulocyte lysate
PJM Murphy, KC Kanelakis, MD Galigniana… - Journal of Biological …, 2001 - ASBMB
Rabbit reticulocyte lysate contains a multiprotein chaperone system that assembles the
glucocorticoid receptor (GR) into a complex with hsp90 and converts the hormone binding …
glucocorticoid receptor (GR) into a complex with hsp90 and converts the hormone binding …
[HTML][HTML] Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery
KC Kanelakis, Y Morishima, KD Dittmar… - Journal of Biological …, 1999 - ASBMB
The heat shock protein hsp70/hsc70 is a required component of a five-protein (hsp90, hsp70,
Hop, hsp40, and p23) minimal chaperone system reconstituted from reticulocyte lysate that …
Hop, hsp40, and p23) minimal chaperone system reconstituted from reticulocyte lysate that …
Benzimidazole-2-pyrazole HIF prolyl 4-hydroxylase inhibitors as oral erythropoietin secretagogues
…, HM Peltier, SD Bembenek, KC Kanelakis… - ACS medicinal …, 2010 - ACS Publications
HIF prolyl 4-hydroxylases (PHD) are a family of enzymes that mediate key physiological
responses to hypoxia by modulating the levels of hypoxia inducible factor 1-α (HIF1α). Certain …
responses to hypoxia by modulating the levels of hypoxia inducible factor 1-α (HIF1α). Certain …
Prolyl hydroxylase inhibition corrects functional iron deficiency and inflammation‐induced anaemia in rats
…, TI Brondstetter, KC Kanelakis… - British Journal of …, 2015 - Wiley Online Library
… This article was written by Kimon C. Kanelakis in his private capacity. No official support or …
related enzyme FIH was assessed as previously described (Kanelakis et al., 2009; Barrett et al…
related enzyme FIH was assessed as previously described (Kanelakis et al., 2009; Barrett et al…
Did you mean to search for: Kimon. Kanellakis