[PDF][PDF] Massive and reproducible production of liver buds entirely from human pluripotent stem cells

…, S Ogawa, M Ishikawa, Y Kiyota, Y Sato, K Nozawa… - Cell reports, 2017 - cell.com
Organoid technology provides a revolutionary paradigm toward therapy but has yet to be
applied in humans, mainly because of reproducibility and scalability challenges. Here, we …

R-htdetector: Robust hardware-trojan detection based on adversarial training

K Hasegawa, S Hidano, K Nozawa… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Hardware Trojans (HTs) have become a serious problem, and extermination of them is strongly
required for enhancing the security and safety of integrated circuits. An effective solution …

Formation of the accumulative human metabolite and human-specific glutathione conjugate of diclofenac in TK-NOG chimeric mice with humanized livers

H Kamimura, S Ito, K Nozawa, S Nakamura… - Drug Metabolism and …, 2015 - ASPET
3′-Hydroxy-4′-methoxydiclofenac (VI) is a human-specific metabolite known to accumulate
in the plasma of patients after repeated administration of diclofenac sodium. Diclofenac …

Rigidins B−D, New Pyrrolopyrimidine Alkaloids from a Tunicate Cystodytes Species

M Tsuda, K Nozawa, K Shimbo… - Journal of natural …, 2003 - ACS Publications
Kohei NozawaKohei Nozawa - Graduate School of Pharmaceutical Sciences,
Hokkaido University, Sapporo 060-0812, Japan … Kohei Nozawa, Masashi Tsuda, Haruaki …

Absolute stereochemistry and antitumor activity of iejimalides

K Nozawa, M Tsuda, H Ishiyama, T Sasaki… - Bioorganic & medicinal …, 2006 - Elsevier
The absolute configurations at five chiral centers, except for C-32(S) reported previously, in
iejimalides A, C, and D, potent cytotoxic 24-membered macrolides isolated from a tunicate …

3.1–5.2 μm coherent MIR frequency comb based on Yb-doped fiber laser

…, H Tomita, T Iguchi, A Sato, K Nozawa… - IEEE Journal of …, 2017 - ieeexplore.ieee.org
An offset-free, wavelength-tunable, and midinfrared frequency comb working at 184 MHz
based on difference frequency generation (DFG) in a PPMgSLT crystal was demonstrated. A …

New Frontiers—Accelerator Mass Spectrometry (AMS): Recommendation for Best Practices and Harmonization from Global Bioanalysis Consortium Harmonization …

…, SR Dueker, P Timmerman, A Arjomand, K Nozawa - The AAPS journal, 2014 - Springer
The technique of accelerator mass spectrometry (AMS) is applicable to the analysis of a wide
range of trace elemental isotopes. However, in the context of the pharmaceutical industry, it …

Generating adversarial examples for hardware-trojan detection at gate-level netlists

K Nozawa, K Hasegawa, S Hidano… - Journal of information …, 2021 - jstage.jst.go.jp
Recently, the great demand for integrated circuits (ICs) drives third parties to be involved in
IC design and manufacturing steps. At the same time, the threat of injecting a malicious circuit…

Adversarial examples for hardware-trojan detection at gate-level netlists

K Nozawa, K Hasegawa, S Hidano, S Kiyomoto… - … Security: ESORICS 2019 …, 2020 - Springer
Recently, due to the increase of outsourcing in integrated circuit (IC) design and manufacturing,
the threat of injecting a malicious circuit, called a hardware Trojan, by third party has …

Stereochemistry of iejimalide B

M Tsuda, K Nozawa, K Shimbo, H Ishiyama, E Fukushi… - Tetrahedron letters, 2003 - Elsevier
The absolute configurations at five chiral centers, except for C-32(S) reported previously, in
iejimalide B (1), a potent cytotoxic 24-membered macrolide isolated from a tunicate …