[PDF][PDF] Metabolism of vitamin D3 by cytochromes P450

T Sakaki, N Kagawa, K Yamamoto, K Inouye - Front Biosci, 2005 - article.imrpress.com
Inouye: Metabolic studies using recombinant escherichia coli cells producing rat
mitochondrial CYP24: CYP24 can convert 1alpha,25-dihydroxyvitamin D3 to calcitroic acid. Eur J …

Review on utilization and composition of coffee silverskin

Y Narita, K Inouye - Food Research International, 2014 - Elsevier
Coffee is one of the most frequently consumed drinks in the world. Coffee silverskin (CS) is
the only by-product produced during the coffee beans roasting process, and large amounts of …

Functional properties of soy protein hydrolysates obtained by selective proteolysis

…, K Tsuge, H Ashida, W Kugimiya, K Inouye - LWT-Food Science and …, 2005 - Elsevier
Soy protein hydrolysates were produced from a soy protein isolate (SPI) in which either the
glycinin or β-conglycinin fractions had been selectively hydrolysed. The solubility, apparent …

Enzymatic studies on the key enzymes of vitamin D metabolism; 1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24)

K Inouye, T Sakaki - 2001 - Elsevier
The key enzymes of vitamin D 3 metabolism, renal 25-hydroxyvitamin D 3 1α-hydroxylase (CYP27B1)
and 24-hydroxylase (CYP24) were expressed in Escherichia coli, and their …

Use of Bombyx mori silk fibroin as a substratum for cultivation of animal cells

K Inouye, M Kurokawa, S Nishikawa… - Journal of biochemical …, 1998 - Elsevier
The growth of animal cells on silk fibroin-coated plates was examined. The anchorage-dependent
cells showed almost the same growth on both fibroin- and collagen-coated plates, and …

Dual metabolic pathway of 25‐hydroxyvitamin D3 catalyzed by human CYP24

…, K Yamamoto, Y Ohyama, K Inouye - European journal of …, 2000 - Wiley Online Library
Human 25‐hydroxyvitamin D 3 (25(OH)D 3 ) 24‐hydroxylase (CYP24) cDNA was
expressed in Escherichia coli, and its enzymatic and spectral properties were revealed. The …

[HTML][HTML] Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis …

…, M Nagayoshi, R Shinkyo, T Sakaki, K Inouye… - Journal of Biological …, 2003 - ASBMB
Two cytochrome P450 (P450) cDNAs involved in the biosynthesis of berberine, an
antimicrobial benzylisoquinoline alkaloid, were isolated from cultured Coptis japonica cells and …

[HTML][HTML] C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and …

…, S Hatakeyama, T Sakaki, N Sawada, K Inouye… - Journal of Biological …, 2004 - ASBMB
Recently, it was revealed that 1α,25-dihydroxyvitamin D 3 (1α,25(OH) 2 D 3 ) and 24R,25-dihydroxyvitamin
D 3 (24,25(OH) 2 D 3 ) were metabolized to their respective epimers of the …

Metabolism of vitamin D by human microsomal CYP2R1

…, T Sakaki, M Kamakura, M Ohta, K Inouye - … and biophysical research …, 2004 - Elsevier
The activation of vitamin D requires 25-hydroxylation in the liver and 1α-hydroxylation in the
kidney. However, it remains unclear which enzyme is relevant to vitamin D 25-hydroxylation. …

Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas α-amylase isozymes I and II

Y Narita, K Inouye - Journal of Agricultural and Food Chemistry, 2009 - ACS Publications
Chlorogenic acid (5-caffeoylquinic acid, 5-CQA) is a kind of polyphenol and is richly included
in green coffee beans. The inhibitory effects of 5-CQA and its components, caffeic acid (CA…