Cleavage of amyloid precursor protein (APP) by the β- and γ-secretases generates the
amino and carboxy termini, respectively, of the Aβ amyloidogenic peptides Aβ40 and Aβ42—the …

The avian skeletal α-actin gene was used as a template for construction of a myogenic
expression vector that was utilized to direct expression of a human IGF-I cDNA in cultured muscle …

γ-Secretase is a membrane-associated protease that cleaves within the transmembrane
region of amyloid precursor protein to generate the C termini of the two Aβ peptide isoforms, …

The mechanism underlying subcutaneous absorption of macromolecules and factors that
can influence this process were studied in rats using PEGylated erythropoietins (EPOs) as …

β-Secretase (BACE) is a membrane-bound aspartyl protease that cleaves the amyloid
precursor protein to generate the N terminus of the amyloid β peptide. BACE is expressed as a …

N 1 -guanyl-1,7-diaminoheptane (GC 7 ) is a potent inhibitor of deoxyhypusine synthase (DHS),
the enzyme that catalyzes the first step in the hypusination of eukaryotic translation …

Parkinson’s disease (PD) is an acute and progressive neurodegenerative disorder, and
diagnosis of the disease at its earliest stage is of paramount importance to improve the life …

Patients in the do Tirofiban And Reopro Give similar Efficacy outcomes Trial (TARGET)
treated with abciximab compared with tirofiban had a lower 30-day incidence of the combined …

To gain insight into the role of the eukaryotic translation initiation factor, eIF-5A, we investigated
the subcellular distribution of this protein in several cultured cell types and at different …

Erythropoietin (EPO) is an important molecule in the erythropoiesis and various forms of EPO
have been marketed in managing anemia in humans. Long acting EPOs for less frequent …