Hyaluronan-conjugated liposomes encapsulating gemcitabine for breast cancer stem cells

NK Han, DH Shin, JS Kim, KY Weon… - International journal …, 2016 - Taylor & Francis
Investigation of potential therapeutics for targeting breast cancer stem cells (BCSCs) is
important because these cells are regarded as culprit of breast cancer relapse. Accomplishing …

Pharmaceutical application and development of fixed-dose combination: Dosage form review

DW Kim, KY Weon - Journal of Pharmaceutical Investigation, 2021 - Springer
Background Fixed dose combination (FDC) products are common in the treatment of various
disease such as hypertension, diabetes, HIV and HCV, Pain, Respiratory disease for …

[HTML][HTML] Non-invasive photodynamic therapy against-periodontitis-causing bacteria

D Park, EJ Choi, KY Weon, W Lee, SH Lee, JS Choi… - Scientific reports, 2019 - nature.com
Periodontitis is initiated by causative bacteria in the gingival sulcus. However, as the lesion
is often deep and out of circulation system and biofilm is frequently formed on the bacteria …

Determination of acrylamide and glycidamide in various biological matrices by liquid chromatography–tandem mass spectrometry and its application to a …

…, S Shin, KB Kim, WS Seo, JC Shin, JH Choi, KY Weon… - Talanta, 2015 - Elsevier
Acrylamide (AA) is a heat-generated food toxicant formed when starchy foods are fried or
baked. This study describes a simple and sensitive liquid chromatography–tandem mass …

[HTML][HTML] 3D-printed gastroretentive sustained release drug delivery system by applying design of experiment approach

HM Jeong, KY Weon, BS Shin, S Shin - Molecules, 2020 - mdpi.com
This study aimed to develop a novel oral drug delivery system for gastroretentive sustained
drug release by using a capsular device. A capsular device that can control drug release …

Restoration of paclitaxel resistance by CDK1 intervention in drug-resistant ovarian cancer

T Bae, KY Weon, JW Lee, KH Eum, S Kim… - …, 2015 - academic.oup.com
Epithelial ovarian cancer (EOC) commonly acquires resistance to chemotherapy, and this is
the major obstacle to the better prognosis. Elucidating the molecular targets altered by …

Anionic amino acid-derived cationic lipid for siRNA delivery

…, YH Yu, Y Choi, K Kim, IC Kwon, KY Weon… - Journal of controlled …, 2009 - Elsevier
Viable siRNA therapeutic strategies require the concurrent development of effective and
safe delivery systems. Here, we described the synthesis of a new cationic lipid, N,N″-…

Development of a docetaxel micellar formulation using poly (ethylene glycol)–polylactide–poly (ethylene glycol)(PEG–PLA–PEG) with successful reconstitution for …

…, ES Lee, YS Youn, HG Choi, HK Han, KY Weon… - Drug …, 2018 - Taylor & Francis
Docetaxel (DTX)-loaded polymeric micelles (DTBM) were formulated using the triblock
copolymer, poly(ethylene glycol)–polylactide–poly(ethylene glycol) (PEG–PLA–PEG), to …

Anti-inflammatory activity of phenolic compounds from the whole plant of Scutellaria indica

TD Cuong, TM Hung, JS Lee, KY Weon… - Bioorganic & medicinal …, 2015 - Elsevier
Six new phenolics, scutellariosides A–F (1–3, 5–6, and 8), together with six known compounds
(4, 7, 9–12) were isolated from the whole plant of Scutellaria indica (Labiatae). The …

Cytotoxic triterpenoids from the fruits of Ligustrum japonicum

…, TQ Cao, MH Woo, BS Min, KY Weon - Natural Product …, 2018 - synapse.koreamed.org
Medicinal plants are potential sources of anticancer agents screening. A large number of
phytochemicals, including triterpenoids, have been reported to have significant cytotoxic effects …