In order to obtain a better structural framework for understanding the catalytic mechanism of
carbonic anhydrase, a number of inhibitor complexes of the enzyme were investigated …

CATECHOL O-methyltransferase (COMT, EC 2.1.1.6) is important in the central nervous
system because it metabolizes catecholamine neurotransmitters such as dopamine. The …

The crystal structure of Thermus thermophilus elongation factor G without guanine nucleotide
was determined to 2.85 A. This GTPase has five domains with overall dimensions of 50 × …

… Results of the analysis of multiple conformations were reported previously (Svensson et
al., 1987) on the basis of the model after refinement cycle 86. An additional 17 cycles of …

A new X-ray crystallographic beamline is operational at the MAX II synchrotron in Lund. The
beamline has been in regular use since August 1998 and is used both for macro- and small …

… Anders Svensson … Anders Svensson - Laboratory of Biomolecular Structure and Dynamics,
and Department of Inorganic Chemistry, Faculty of Science, Masaryk University, Kotlárská 2, …

Hemophilia is treated by IV replacement therapy with Factor VIII (FVIII) or Factor IX (FIX),
either on demand to resolve bleeding, or as prophylaxis. Improved treatment may be provided …

Staphylococcal enterotoxins are prototype superantigens characterized by their ability to bind
to major histocompatibility complex (MHC) class II molecules and subsequently activate a …

Synthesis and structure−activity relationships of tricyclic α-ethoxy-phenylpropionic acid
derivatives guided by in vitro PPARα and PPARγ transactivation data and computer modeling led …

In a structure of recombinant bovine calbindin D 9k , determined crystallographically to 1.6 Å
resolution, a proline in mixed, approximately equally populated, cis and trans conformation …